Was it carbs? Fat? Genetics? Willpower? Metabolism? So many competing theories, so much conflicting data.
Then came drugs like Ozempic and Wegovy—and they ran the experiment for us.
Millions of people who swore they couldn’t lose weight started losing weight. Same people. Same genes. Same lives.
GLP-1 drugs didn’t just create a new treatment for obesity. They ended a debate.
Turns out when you give people a tool that actually reduces appetite, they eat less and lose weight.
Almost like it was a calorie problem all along.
Don’t believe me?
GLP-1s have already dismembered several of the most common excuses for staying fat.
“It’s my genetics.”
Scientists have identified specific genes that make people hungrier, harder to satisfy after eating, and more drawn to junk food.
The most common one is called MC4R, and it indeed produces real, measurable biological disadvantages that predispose carriers to obesity.
But GLP-1 research shows the drugs work just as well for people with this “obesity gene” as for everyone else. Similar findings have been demonstrated in people carrying other genes associated with fatness.
So, while DNA might help explain why someone got fat, it doesn’t stop them from losing weight when they eat less food.
“It’s my menopause and/or PCOS.”
For many women, menopause feels like the fat loss final boss on Nightmare Mode.
But then GLP-1 data showsthese drugs work just as well for menopausal women as for younger ones.
And in women with polycystic ovary syndrome (PCOS)—a hormonal condition linked to weight gain and insulin problems—GLP-1s produce meaningful weight loss and improvements in blood sugar.
“It’s my medication.”
Many psychiatric drugs cause serious weight gain. For instance, clozapine is used to treat severe schizophrenia, and it packs on the pounds.
A recent trial gave these patients Ozempic-style drugs alongside their psychiatric medication. And they lost weight. And their psychiatric symptoms didn’t get worse.
“It’s my crazy appetite.”
Some people don’t just have mysteriously outsized appetites—the “hunger center” of their brain is damaged.
For these people, appetite isn’t just hard to manage—the control system itself is physically broken.
And yet in one case series of four women with this kind of brain damage, they lost ~17% of their body weight on these drugs and kept it off for two years.
The bottom line?
The pattern keeps repeating.
Researchers test GLP-1 drugs on people with rare genetic syndromes that cause extreme hunger. They work. They test them on people with hormone disorders. They work. They test them on people whose obesity seemed completely hopeless. They work.
So far, the primary variables that actually affect how well these drugs work appear to be:
Whether you’re male or female
Whether you have diabetes
How heavy you are when you start
Whether you keep taking them
That’s it. Not your genes. Not your thyroid. Not your hormones. Not menopause.
Thus, the existence of GLP-1 drugs proves that for 99% of people, the “root cause” of their obesity isn’t a mysterious metabolic glitch, a thyroid issue, or a toxin.
Simply let us know, and you'll get a full refund, no questions asked. And you don't even need to return anything.
So that means you can say "yes" now and decide later.
Why do we have a $99 free shipping threshold?
Because shipping a single item is surprisingly expensive.
So blasted expensive, in fact, that on a small order, the shipping cost alone can eat up all of the profits.
However, the economics change dramatically when you bundle, because adding a second or third item to your order costs us very little extra to ship.
And once your order hits the $99 mark (a few items), the math works out, and we can cover the entire shipping cost for you.
Why the $199 minimum purchase amount for free shipping?
To quench our piggish lust for grubby profits in the eternal service of the dread lord Mammon?
Kind of. But not really. Because here's the truth:
Single-item orders are so blasted expensive to ship that we make very little profit on them. And no profits make the bean counters lose their marbles.
But when you order just one more item, it only costs us a few dollars more to ship both of them to you. Add a third item, and it's just a few more shekels to ship.
And that allows us to make a profit. Which keeps the bean counters happier than a hammer in a nail factory.
So, if it pleases your Grace, we humbly request your mercy and patronage notwithstanding the vexing free shipping minimum.
Why the $299 minimum purchase amount for free shipping?
To quench our piggish lust for grubby profits in the eternal service of the dread lord Mammon?
Kind of. But not really. Because here's the truth:
Single-item orders are so blasted expensive to ship that we make very little profit on them. And no profits make the bean counters lose their marbles.
But when you order just one more item, it only costs us a few dollars more to ship both of them to you. Add a third item, and it's just a few more shekels to ship.
And that allows us to make a profit. Which keeps the bean counters happier than a hammer in a nail factory.
So, if it pleases your Grace, we humbly request your mercy and patronage notwithstanding the vexing free shipping minimum.
Wait! Want to save 50% on your order of Legion supplements?
Use code NASM25 at checkout!
Buy one supplement, get one 50% off when you use code LEGION10 at checkout.
No thanks, I don't want to save on my order.
You're Back! We've Missed You!
Blare the trumpets and beat the drums because you get 20% off your next order!
Simply use the code COMEBACK20 at checkout to unlock instant savings.
Split your entire online purchase into 4 interest-free payments, over 6 weeks with no impact to your credit.
25% today
25% 2 weeks
25% 4 weeks
25% 6 weeks
Here's how to Sezzle
Shop
Shop and add items to your cart as normal!
Checkout
Choose Sezzle at Checkout! You’ll be redirected to Sezzle to Sign Up or Log In
to complete your order.
Sezzle it
Your order will be shipped out right away* and your payments will be split up
over 6 weeks.
*shipping times subject to merchant shipping policy
Download the App
Shop directory. Reschedule payments. Plus more!
Waiver and Release of Liability
In consideration of the services and/or products offered by Legion Athletics, Inc. (“Legion”) including, but not limited to, nutrition plans, exercise routines and coaching, and in addition to the payment of any fee or charge:
I knowingly and voluntarily enter into this waiver and release of liability and hereby waive any and all rights, claims or causes of action of any kind whatsoever arising out of my use of Legion’s services and/or products, and I hereby release and hold harmless Legion and its consultants, officers, contractors, agents, owners and employees from any and all responsibility, liability, cost and expenses, including for injuries, damages or disorders (physical, metabolic, or otherwise), resulting from my use of Legion’s services and/or products.
I understand that fitness activities including, but not limited to, strength, flexibility, and cardiovascular exercise, with or without the use of equipment, are potentially hazardous activities that involve a risk of injury and even death, and I am voluntarily participating in these activities and using equipment and machinery with knowledge of the risks involved. I hereby agree to assume and accept any and all risks of injury or death related to said fitness activities.
I understand Legion’s services and products are not meant to treat or manage any health conditions or circumstances, and I acknowledge that Legion has recommended I obtain a healthcare provider’s approval for my use of Legion’s services and/or products, through regular physical examination(s) and/or consultation. I acknowledge that I have obtained my healthcare provider’s approval or have decided to use Legion’s services and/or products without such approval and hereby assume all responsibility for my use of said services and/or products.
I understand that results from using Legion’s products and/or services are not guaranteed, and I agree to not hold Legion liable for any outcomes or lack thereof.
OUT OF STOCK
Great! You're subscribed!
Looks like you're already subscribed!
Security Check
Please click the checkbox below. We apologize for the inconvenience.
Legion's Scientific Review Process
Legion's content is fact-checked and reviewed by a team of scientific, medical and subject-matter experts to ensure everything we publish is evidence based, trustworthy, and current.
Our scientific review board of nutritionists, dietitians, molecular biologists, doctors, and other accredited experts is responsible for reviewing every article, podcast, and video we produce to ensure they’re evidence based, accurate, trustworthy, and current.
Thanks to their connections, credentials, and academic experience, this team of MDs, PhDs, and other professionals has access to a wealth of research published in the largest and most prestigious journals in the world.
This allows them to not only review individual studies but also analyze the overall weight of the evidence on any and all topics related to diet, exercise, supplementation, and more.
If you feel that any of our content is inaccurate, misleading, out-of-date, or anything less than factual, please let us know in the comments section of the article in question.
Evidence Based
We follow a detailed, rigorous, multi-step process to create content that meets the highest standards of clarity, practicality, and scientific integrity.
First, our research associates provide our editorial team with accurate, up-to-date, proven scientific evidence.
Then, our editorial team uses this research to draft articles and outlines for podcasts and videos.
Finally, our scientific review board reviews the content to ensure all key information and claims are backed by high-quality scientific research and explained simply and precisely.
If you feel that any of our content is inaccurate, misleading, out-of-date, or anything less than factual, please let us know in the comments section of the article in question.
We and our partners use technology, including cookies, to view and retain your site interactions, enable site functionality, enhance user experience, perform analytics, and assist our marketing efforts as described in our Privacy Policy.
