Our "No Return Necessary"
Money-Back Guarantee

If you don’t like something of ours, guess what happens next?

No, we don’t request you deliver it to a PO box in the Gobi Desert by carrier pigeon. Nor do we ask you to fill a cursed inkwell with orc’s blood and demon saliva and then use it to complete reams of return forms written in ancient Cyrillic script.

We just . . . wait for it . . . give you your money back. Holy moo cows. And that means you can say "yes" now and decide later.

Will Energy Surge kick your metabolism into overdrive and unlock all-day pep and power?

No.

Will it ignite your mind and transform your mood?

Absolutely not.

But is Energy Surge the only[1] Some popular energy supplements are all-natural. Some contain the right mix of high-quality ingredients. Some provide clinically effective doses. But only Energy Surge checks each of these boxes. natural[2] Energy Surge doesn’t just “contain natural ingredients''—every ingredient is naturally sourced from plants and animals. Energy Surge contains no artificial or synthetic substances of any kind. energy supplement with clinically effective doses[3] Every serving of Energy Surge contains 2.47 grams of active ingredients that have been shown to be safe and effective in peer-reviewed scientific research. of 5 ingredients scientifically shown[4] Each active ingredient in Energy Surge is backed by published scientific studies that show benefits in healthy humans. to boost energy, performance, mood, and focus, and reduce fatigue?

And will it help you feel livelier, sharper, and calmer without a crash or other unwanted side effects?

Yes. Or your money back.

  • 36 peer-reviewed scientific studies support Energy Surge’s combination of ingredients and doses[5] That’s 304 pages of scientific research that shows Energy Surge works exactly like we say it does.
  • Contains no artificial sweeteners, flavors, food dyes, or other chemical junk[6] While these types of chemicals may not be as dangerous as some people claim, studies suggest that regular consumption of them may indeed be harmful to our health. And that’s why you won’t find them in Energy Surge.
  • Analyzed for purity and potency in a state-of-the-art ISO 17025 accredited lab[7] Every bottle of Energy Surge is guaranteed to provide exactly what the label claims and nothing else—no heavy metals, microbes, allergens, or other contaminants.
  • Total formulation transparency (no proprietary blends)[8] This means you know exactly what’s in every serving of Energy Surge—every dose of every ingredient—and can verify the accuracy and efficacy of the formulation.
  • Made in the USA with globally sourced ingredients in NSF-certified and FDA-inspected facilities that adhere to Current Good Manufacturing Practice standards

Energy Surge is also backed by our “No Return Necessary” money-back guarantee that works like this:

If you don’t absolutely love Energy Surge, just let us know, and we’ll give you a full refund on the spot. No forms or returns necessary.

So order now, try Energy Surge risk free, and see for yourself why we believe it’s the perfect low-stimulant alternative (or addition) to coffee or a pre-workout supplement.

Will Energy Surge kick your metabolism into overdrive and unlock all-day pep and power?

No.

Will it ignite your mind and transform your mood?

Absolutely not.

But will Energy Surge help you feel livelier, sharper, and calmer without a crash or other unwanted side effects?

Yes. Or your money back.

  • Total formulation transparency (no proprietary blends)[8] This means you know exactly what’s in every serving of Energy Surge—every dose of every ingredient—and can verify the accuracy and efficacy of the formulation.
  • Made in the USA with globally sourced ingredients in NSF-certified and FDA-inspected facilities that adhere to Current Good Manufacturing Practice standards
  • Backed by our “No Return Necessary” money-back guarantee that works like this: If you don’t absolutely love Energy Surge, just let us know, and we’ll give you a full refund on the spot. No forms or returns necessary.

So order now, try Energy Surge risk free, and see for yourself why we believe it’s the perfect low-stimulant alternative (or addition) to coffee or a pre-workout supplement.

Notice to California Consumers

WARNING: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Legion Energy Surge Ingredients (2.47 grams per serving)

Caffeine Anhydrous (100 milligrams per serving)

Caffeine is a naturally occurring substance found in many plants native to Africa, East Asia, and South America, including various kinds of tea, cocoa, and coffee.

Caffeine’s primary effects in the body are to stimulate the central nervous system and block the activity of another chemical—adenosine—that causes tiredness.

Research shows that supplementation with caffeine . . .

The clinically effective dose of caffeine for enhancing energy, focus, and performance is between 1 and 6 milligrams per kilogram of body weight.[27][28][29]

Caffeine

Suntheanine® L-Theanine (100 milligrams per serving)

L-theanine is an amino acid found primarily in tea that helps balance the levels of two chemicals in the brain—glutamate and GABA—that transmit nerve impulses and affect mood, cognitive performance, and more.

Research shows that supplementation with L-theanine . . .

  • Reduces the effects of mental stress[30]
  • Promotes relaxation[31]
  • Improves mood, memory performance, and attention (When paired with caffeine)[32][33][34][35]
  • Increases the production of nitric oxide (which improves blood flow)[36]

The clinically effective dose of L-theanine when combined with caffeine is between a ratio of 1:1 and 2:1 theanine to caffeine.

L-Theanine

Taurine (2 grams per serving)

Taurine is an amino acid found primarily in seafood and meat that plays an important role in cardiovascular and muscle function by protecting cells from oxidative stress and regulating the release of neurotransmitters and glucose.[37][38]

Research shows that supplementation with taurine . . .

  • Improves focus, attention, and verbal reasoning when combined with caffeine[39][40]
  • Helps minimize unwanted side effects of caffeine (like jitters)[41]
  • Helps prevent a “sugar crash” by slowing the release of glucose into the blood[42][43]

The clinically effective dose of taurine is 1-to-3 grams.

L-Theanine

Rhodiola Rosea Extract (250 milligrams per serving)

Rhodiola rosea (also known as Golden Root) is a plant that grows in cold parts of the world, including the Arctic regions of Europe, Asia, and North America.

It’s known as an adaptogen, which is a substance that causes an imperceptible level of stress in the body and trains it to better handle future stresses.

Research shows that supplementation with rhodiola rosea . . .

  • Improves mood and reduces symptoms of stress and depression[44][45][46]
  • Reduces stress-related fatigue[47]
  • Preserves and possibly enhances cognition and mood during strenuous periods[48]
  • May enhance physical performance[49]
  • May reduce exercise-induced muscle damage[50]
  • May help the body defend against viral infections[51]

The clinically effective dose of rhodiola rosea is unknown, but most long-term benefits have been observed with 90 to 120 milligrams.

Energy Surge contains 250 milligrams of rhodiola rosea per serving because it may produce quicker results.

Forskolin

B Vitamin Complex (27.4 milligrams per serving)

B vitamins are a category of naturally-occurring substances that cells need to turn food into energy. They also affect mood, feelings of wellness, and brain, nerve, and cardiovascular function.

Research shows that supplementation with B vitamins (particularly vitamins B2, B3, B6, and B12) . . .

  • Reduces stress[52]
  • Improves mental clarity, energy, and focus[53]
  • Boosts cognitive function and memory[54][55]
  • Can prevent and reduce symptoms of depression[56][57]

There is no established clinically effective dose of a B vitamin complex, but the B vitamins thought to most improve energy, mood, and cognitive function are B2, B3, B6, and B12.

Energy Surge contains 3.4 mg of vitamin B2 (as riboflavin), 20 mg of vitamin B3 (as niacin), 4 mg of vitamin B6 (as pyridoxal-5-phosphate), 12 mcg of vitamin B12 (as methylcobalamin).

Fucoxanthin

100% Naturally Sweetened & Flavored

While artificial sweeteners may not be as dangerous as some people claim, studies suggest that regular consumption of these chemicals may indeed be harmful to our health.[58][59][60][61][62][63]

That’s why we use the natural sweeteners stevia and erythritol instead. Studies show that these ingredients are not only safe but can also confer several health benefits, including better insulin sensitivity, enhanced cholesterol profile, lower inflammation levels, and more.[64][65][66][67]

No Artificial Food Dyes or Other Chemical Junk

No Artificial Food Dyes, Fillers, or Other Unnecessary Junk

As with artificial sweeteners, artificial food dyes aren’t a hazard per se, but studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.[68][69][70][71][72]

That’s why we use natural coloring derived from fruits and other foods, as well as natural flavoring.

No Artificial Food Dyes or Other Chemical Junk

Third-Party Lab Tested for Potency & Purity

Every bottle of Energy Surge is analyzed in a state-of-the-art ISO 17025 accredited lab to verify what is and isn’t in it. That way, you know exactly what you’re getting and putting into your body.

Third-Party Lab Tested for Potency & Purity

See how Legion Energy Surge compares to the rest.

  • Active Ingredients
  • Clinically Effective Ingredients & Doses
  • Caffeine Anhydrous
  • L-Theanine
  • Taurine
  • Rhodiloa Rosea Extract
  • Vitamin B Complex
  • Third-Party Lab Tested
  • Labdoor Certified Brand
  • Price Per Serving
  • Legion Energy Surge

    Energy Surge
  • 2,470 mg
    per serving
  • True
  • 100 mg
    per serving
  • 100 mg
    per serving
  • 2,000 mg
    per serving
  • 250 mg
    per serving
  • 27.4 mg
    per serving
  • Question Mark
  • False
  • $
  • Now Sports Energy Extreme

    Energy Extreme
  • 1,395 mg
    per serving
  • False
  • 100 mg
    per serving
  • False
  • 250 mg per serving
  • 50 mg per serving
  • 40 mg per serving
  • Question Mark
  • False
  • $0.62
  • Ghost Gamer

    Ghost Gamer
  • 2,420 mg
    per serving
  • False
  • 75 mg
    per serving
  • False
  • 500 mg per serving
  • False
  • 10 mg per serving
  • Question Mark
  • False
  • $1.00
  • Nutricost Energy Complex

    Nutricost
  • 2,724 mg
    per serving
  • False
  • 80 mg
    per serving
  • 100 mg per serving
  • 750 mg per serving
  • False
  • 26 mg per serving
  • Question Mark
  • False
  • $0.46

The #1 brand of all-natural sports supplements.

Over 5+ million bottles sold to over 1+ million customers who have left us over 45,000 5-star reviews.

Natural Ingredients
Natural Ingredients

Energy Surge doesn’t just “contain natural ingredients”—every ingredient is naturally sourced. We don’t use artificial or synthetic substances of any kind.

Clinically Effective Doses
Clinically Effective Ingredients & Doses

Every ingredient and dose (important!) in Energy Surge is backed by peer-reviewed scientific research demonstrating clear benefits.

Naturally Sweetened & Flavored
Naturally Sweetened & Flavored

Energy Surge is naturally sweetened and flavored with healthy, plant-based sweeteners and flavors.

Lab Tested
Third-Party Lab Tested

Energy Surge is tested by third-party labs for heavy metals, microbes, allergens, and other contaminants to ensure it meets FDA purity standards.

Made in USA
Made in the USA

Energy Surge is made in America with globally sourced ingredients in NSF-certified, FDA-inspected facilities that adhere to Current Good Manufacturing Practice (cGMP) standards.

100% Money-Back-Guarantee
"No Return Necessary"
Money-Back Guarantee

If you don't absolutely love Energy Surge, you get a prompt and courteous refund. No forms or returns necessary.

Trusted by scientists, doctors, and everyday fitness folk alike.

Previous
  • Sal Di Stefano, Justin Andrews, and Adam Schafer

    "When it comes to quality and integrity, Legion is among the best. Their products only include ingredients that are backed by research and in doses that are proven to be effective in scientific studies."

    Sal Di Stefano, Justin Andrews, and Adam Schafer

    Hosts of The Mind Pump Podcast
  • Dr. Bill Campbell, PhD

    "Legion is science-based at its core. Not only do they dose all of their products based on the clinical doses proven to be effective by scientific studies, they go above and beyond the their competitors by funding new research."

    Dr. Bill Campbell, PhD

    Professor of Exercise Science at University of South Florida
  • Jordan Syatt

    "Legion is a tremendous company run by people I trust and respect. The quality of their supplements is second to no one. And while I don’t use many supplements, the only ones I do come from Legion."

    Jordan Syatt

    Strength and Nutrition Coach
  • Dr. Spencer Nadolsky, MD

    "There are a lot of sleazy supplement companies out there, but Legion is not one of them. Their products are free of fillers and inactive ingredients and they take the time (and money) to test them with independent labs to ensure you're getting what you pay for."

    Dr. Spencer Nadolsky, MD

    Board-Certified Family Medicine Physician and a Diplomate of the American Board of Obesity Medicine
  • Menno Henselmans, MS

    "Legion consults with nutrition experts to make honest, science-based products and then proves they're genuine with independent lab work. That's how all supplement companies should operate."

    Menno Henselmans, MS

    Founder of Bayesian Bodybuilding, Published Scientist, and Physique Coach
  • Kurtis Frank

    "With Legion, you really do get what you pay for. Each and every product is packed with effective doses of effective ingredients, and what’s on the label is what's actually in the bottle."

    Kurtis Frank

    Co-Founder and Former Lead Researcher & Writer of Examine.com
  • James Krieger, MS

    "There are three reasons I like Legion. First, they use ingredients backed by independent, peer-reviewed scientific studies. Second, the quality of their supplements exceeds many in the industry and you know you’re getting what’s on the label. Third, Mike Matthews is a solid evidence-based guy who doesn’t over-hype."

    James Krieger, MS

    Published Scientist, Author, and Speaker
  • Chris Barakat, MS

    "Legion is the only company doing everything right. They make effective products that are backed by scientific evidence, properly dose all of their ingredients, source every ingredient from the highest-quality sources, and are transparent about exactly what goes in each and every product."

    Chris Barakat, MS

    Published Scientist and Physique Coach
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Energy Surge COA

Frequently Asked Questions

How do I use Energy Surge?
Why is Energy Surge unflavored?
Will Energy Surge improve my physical performance?
Can I take Energy Surge every day?
Will I experience a “crash” after taking Energy Surge?
How much caffeine can I safely have every day?
How does Energy Surge differ from Pulse? Can I take both at the same time?
Is Energy Surge vegan?
What does the Prop65 warning on the labels mean?

+References

9. Exercise and sport performance with low doses of caffeine.

Spriet LL. Sports Med. 2014;44 Suppl 2(Suppl 2):S175-S184. doi:10.1007/s40279-014-0257-8.

10. A review of caffeine's effects on cognitive, physical and occupational performance.

McLellan TM, Caldwell JA, Lieberman HR. Neurosci Biobehav Rev. 2016;71:294-312. doi:10.1016/j.neubiorev.2016.09.001.

11. Caffeine to optimize cognitive function for military mission-readiness: a systematic review and recommendations for the field.

Crawford C, Teo L, Lafferty L, et al. Nutr Rev. 2017;75(suppl_2):17-35. doi:10.1093/nutrit/nux007.

12. Caffeine improves reaction time, vigilance and logical reasoning during extended periods with restricted opportunities for sleep.

Kamimori GH, McLellan TM, Tate CM, Voss DM, Niro P, Lieberman HR. Psychopharmacology (Berl). 2015;232(12):2031-2042. doi:10.1007/s00213-014-3834-5.

13. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers.

Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J. Am J Clin Nutr. 1990;51(5):759-767. doi:10.1093/ajcn/51.5.759.

14. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.

Beck TW, Housh TJ, Schmidt RJ, Johnson GO, Housh DJ, Coburn JW, Malek MH. Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska-Lincoln. J Strength Cond Res. 2006 Aug;20(3):506-10.

15. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis.

Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8.

16. The effects of caffeine ingestion on isokinetic muscular strength: A meta-analysis.

Grgic J, Pickering C. J Sci Med Sport. 2019;22(3):353-360. doi:10.1016/j.jsams.2018.08.016.

17. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.

Grgic J, Trexler ET, Lazinica B, Pedisic Z. J Int Soc Sports Nutr. 2018;15:11. Published 2018 Mar 5. doi:10.1186/s12970-018-0216-0.

18. Caffeine ingestion enhances Wingate performance: a meta-analysis.

Grgic J. Eur J Sport Sci. 2018;18(2):219-225. doi:10.1080/17461391.2017.1394371.

19. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.

Beck TW, Housh TJ, Schmidt RJ, Johnson GO, Housh DJ, Coburn JW, Malek MH. Department of Nutrition and Health Sciences, Human Performance Laboratory, University of Nebraska-Lincoln. J Strength Cond Res. 2006 Aug;20(3):506-10.

20. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis.

Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8.

21. Acute effect of caffeine consumption on isotonic muscular strength and endurance: A systematic review and meta-analysis.

Polito MD, Souza DB, Casonatto J, Farinatti P. Sci Sports. 2016;31(3):119-128. doi:10.1016/J.SCISPO.2016.01.006.

22. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis.

Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8.

23. Acute effect of caffeine consumption on isotonic muscular strength and endurance: A systematic review and meta-analysis.

Polito MD, Souza DB, Casonatto J, Farinatti P. Sci Sports. 2016;31(3):119-128. doi:10.1016/J.SCISPO.2016.01.006.

24. Effect of caffeine on sport-specific endurance performance: a systematic review.

Ganio MS, Klau JF, Casa DJ, Armstrong LE, Maresh CM. J Strength Cond Res. 2009;23(1):315-324. doi:10.1519/JSC.0b013e31818b979a.

25. Establishing a relationship between the effect of caffeine and duration of endurance athletic time trial events: A systematic review and meta-analysis.

Shen JG, Brooks MB, Cincotta J, Manjourides JD. J Sci Med Sport. 2019;22(2):232-238. doi:10.1016/j.jsams.2018.07.022.

26. The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis.

Southward K, Rutherfurd-Markwick KJ, Ali A. [published correction appears in Sports Med. 2018 Aug 9;:]. Sports Med. 2018;48(8):1913-1928. doi:10.1007/s40279-018-0939-8.

27. The effects of different doses of caffeine on endurance cycling time trial performance.

Desbrow B, Biddulph C, Devlin B, Grant GD, Anoopkumar-Dukie S, Leveritt MD. J Sports Sci. 2012;30(2):115-120. doi:10.1080/02640414.2011.632431.

28. Effect of caffeine on sport-specific endurance performance: a systematic review.

Ganio MS, Klau JF, Casa DJ, Armstrong LE, Maresh CM. J Strength Cond Res. 2009;23(1):315-324. doi:10.1519/JSC.0b013e31818b979a.

29. International society of sports nutrition position stand: caffeine and exercise performance.

Guest NS, VanDusseldorp TA, Nelson MT, et al. J Int Soc Sports Nutr. 2021;18(1). doi:10.1186/S12970-020-00383-4.

30. L-Theanine reduces psychological and physiological stress responses.

Kimura K, Ozeki M, Juneja LR, Ohira H. Biol Psychol. 2007;74(1):39-45. doi:10.1016/j.biopsycho.2006.06.006.

31. In Search of a Safe Natural Sleep Aid.

Rao TP, Ozeki M, Juneja LR. J Am Coll Nutr. 2015;34(5):436-447. doi:10.1080/07315724.2014.926153.

32. Psychological effects of dietary components of tea: caffeine and L-theanine.

Bryan J. School of Psychology, University of South Australia, Adelaide, 5001, South Australia, Australia. Nutr Rev. 2008 Feb;66(2):82-90.

33. L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.

Einöther SJ, Martens VE, Rycroft JA, De Bruin EA. Sensation, Perception & Behaviour, Unilever R&D Vlaardingen, Vlaardingen, The Netherlands. Appetite. 2010 Apr;54(2):406-9.

34. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task.

Gomez-Ramirez M, Kelly SP, Montesi JL, Foxe JJ. Program in Cognitive Neuroscience and Schizophrenia, The Cognitive Neurophysiology Laboratory, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA. Brain Topogr. 2009 Jun;22(1):44-51.

35. l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.

Kahathuduwa CN, Dhanasekara CS, Chin S-H, et al. Nutr Res. 2018;49:67-78. doi:10.1016/j.nutres.2017.11.002.

36. L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.

Siamwala JH, Dias PM, Majumder S, Joshi MK, Sinkar VP, Banerjee G, Chatterjee S. Vascular Biology Lab, AU-KBC Research Centre, Anna University, MIT Campus, Chennai, India. J Nutr Biochem. 2013 Mar;24(3):595-605.

37. Role of taurine in the central nervous system.

Wu JY, Prentice H. J Biomed Sci. 2010;17 Suppl 1(Suppl 1):S1. Published 2010 Aug 24. doi:10.1186/1423-0127-17-S1-S1.

38. Effects of taurine on plasma glucose concentration and active glucose transport in the small intestine.

Tsuchiya Y, Kawamata K. Anim Sci J. 2017;88(11):1763-1767. doi:10.1111/asj.12829.

39. An evaluation of a caffeinated taurine drink on mood, memory and information processing in healthy volunteers without caffeine abstinence.

Warburton DM, Bersellini E, Sweeney E. Psychopharmacology (Berl). 2001;158(3):322-328. doi:10.1007/s002130100884.

40. A taurine and caffeine-containing drink stimulates cognitive performance and well-being.

Seidl R, Peyrl A, Nicham R, Hauser E. Amino Acids. 2000;19(3-4):635-642. doi:10.1007/s007260070013.

41. Effects and Mechanisms of Taurine as a Therapeutic Agent.

Schaffer S, Kim HW. Biomol Ther (Seoul). 2018;26(3):225-241. doi:10.4062/biomolther.2017.251.

42. The Effect of Taurine on the Glucose Absorption in the Small Intestine.

Tsuchiya Y, Kawamata K. 2015:164. doi:10.11428/KASEI.67.0_164.

43. Effects and Mechanisms of Taurine as a Therapeutic Agent.

Schaffer S, Kim HW. Biomol Ther (Seoul). 2018;26(3):225-241. doi:10.4062/biomolther.2017.251.

44. The Effect of Taurine on the Glucose Absorption in the Small Intestine.

Tsuchiya Y, Kawamata K. 2015:164. doi:10.11428/KASEI.67.0_164.

45. Effects of taurine on plasma glucose concentration and active glucose transport in the small intestine.

Tsuchiya Y, Kawamata K. Anim Sci J. 2017;88(11):1763-1767. doi:10.1111/asj.12829.

46. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms.

Cropley M, Banks AP, Boyle J. Phyther Res. 2015;29(12):1934-1939. doi:10.1002/ptr.5486.

47. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression.

Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian A. Nord J Psychiatry. 2007;61(5):343-348. doi:10.1080/08039480701643290.

48. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.

Mao JJ, Xie SX, Zee J, et al. Phytomedicine. 2015;22(3):394-399. doi:10.1016/j.phymed.2015.01.010.

49. The effects of an acute dose of Rhodiola rosea on endurance exercise performance.

Noreen EE, Buckley JG, Lewis SL, Brandauer J, Stuempfle KJ. J Strength Cond Res. 2013;27(3):839-847. doi:10.1519/JSC.0b013e31825d9799.

50. Effects of chronic Rhodiola Rosea supplementation on sport performance and antioxidant capacity in trained male: preliminary results.

Parisi A, Tranchita E, Duranti G, et al. J Sports Med Phys Fitness. 2010;50(1):57-63.

51. Rhodiola inhibits dengue virus multiplication by inducing innate immune response genes RIG-I, MDA5 and ISG in human monocytes.

Diwaker D, Mishra KP, Ganju L, Singh SB. Arch Virol. 2014;159(8):1975-1986. doi:10.1007/s00705-014-2028-0.

52. The effect of 90 day administration of a high dose vitamin B-complex on work stress.

Stough C, Scholey A, Lloyd J, Spong J, Myers S, Downey LA. Hum Psychopharmacol. 2011;26(7):470-476. doi:10.1002/hup.1229.

53. Thiamine supplementation mood and cognitive functioning.

Benton D, Griffiths R, Haller J. Psychopharmacology (Berl). 1997;129(1):66-71. doi:10.1007/s002130050163.

54. Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms.

Walker JG, Batterham PJ, Mackinnon AJ, et al. The Beyond Ageing Project: a randomized controlled trial [published correction appears in Am J Clin Nutr. 2012 Aug;96(2):448. Dosage error in article text]. Am J Clin Nutr. 2012;95(1):194-203. doi:10.3945/ajcn.110.007799.

55. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.

Deijen JB, van der Beek EJ, Orlebeke JF, van den Berg H. Psychopharmacology (Berl). 1992;109(4):489-496. doi:10.1007/BF02247729.

56. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time.

Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Am J Clin Nutr. 2010;92(2):330-335. doi:10.3945/ajcn.2010.29413.

57. Vitamin B12 supplementation in treating major depressive disorder: a randomized controlled trial.

Syed EU, Wasay M, Awan S. Open Neurol J. 2013;7:44-48. Published 2013 Nov 15. doi:10.2174/1874205X01307010044.

58. Artificial Sweeteners: History and New Concepts on Inflammation.

Basson AR, Rodriguez-Palacios A, Cominelli F. Front Nutr. 2021;8:746247. Published 2021 Sep 24. doi:10.3389/fnut.2021.746247.

59. Non-caloric artificial sweeteners and the microbiome: findings and challenges.

Suez J, Korem T, Zilberman-Schapira G, Segal E, Elinav E. Gut Microbes. 2015;6(2):149-155. doi:10.1080/19490976.2015.1017700.

60. What made Canada become a country with the highest incidence of inflammatory bowel disease: could sucralose be the culprit?

Qin X. Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA. Can J Gastroenterol. 2011 Sep;25(9):511.

61. Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria, E. coli and E. faecalis.

Shil A, Chichger H. Int J Mol Sci. 2021;22(10):5228. Published 2021 May 15. doi:10.3390/ijms22105228.

62. Artificial sweeteners induce glucose intolerance by altering the gut microbiota.

Suez J, Korem T, Zeevi D, et al. Nature. 2014;514(7521):181-186. doi:10.1038/nature13793.

63. High-intensity sweetener consumption and gut microbiome content and predicted gene function in a cross-sectional study of adults in the United States.

Frankenfeld CL, Sikaroodi M, Lamb E, Shoemaker S, Gillevet PM. Ann Epidemiol. 2015;25(10):736-42.e4. doi:10.1016/j.annepidem.2015.06.083.

64. Steviol glycosides from Stevia: biosynthesis pathway review and their application in foods and medicine.

Yadav SK, Guleria P. CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, HP, India. Crit Rev Food Sci Nutr. 2012;52(11):988-98.

65. Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana.

Shivanna N, Naika M, Khanum F, Kaul VK. Department of Applied Nutrition, Defence Food Research Laboratory, Mysore, India. J Diabetes Complications. 2013 Mar-Apr;27(2):103-13.

66. Safety evaluation of certain food additives.

World Health Organization. WHO Press; 2006. Available at: http://whqlibdoc.who.int/publications/2006/9241660546_eng.pdf. Accessed January 24, 2019.

67. Effects of Stevia rebaudiana (Bertoni) extract and N-nitro-L-arginine on renal function and ultrastructure of kidney cells in experimental type 2 Diabetes.

Ozbayer C, Kurt H, Kalender S, Ozden H, Gunes HV, Basaran A, Cakmak EA, Civi K, Kalender Y, Degirmenci I. Department of Medical Biology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey. J Med Food. 2011 Oct;14(10):1215-22.

68. Toxicological significance of azo dye metabolism by human intestinal microbiota.

Feng J, Cerniglia CE, Chen H. Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, AR , USA. Front Biosci (Elite Ed). 2012 Jan 1;4:568-86.

69. Artificial food dyes and attention deficit hyperactivity disorder.

Kanarek RB. Department of Psychology, Tufts University, Medford, Massachusetts, USA. Nutr Rev. 2011 Jul;69(7):385-91.

70. Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives.

Nigg JT, Lewis K, Edinger T, Falk M. Oregon Health and Science University, Portland, OR, USA. J Am Acad Child Adolesc Psychiatry. 2012 Jan;51(1):86-97.e8.

71. Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial.

McCann D, Barrett A, Cooper A, Crumpler D, Dalen L, Grimshaw K, Kitchin E, Lok K, Porteous L, Prince E, Sonuga-Barke E, Warner JO, Stevenson J. School of Psychology, Department of Child Health, University of Southampton, Southampton, UK. Lancet. 2007 Nov 3;370(9598):1560-7.

72. Effect of food azo dye tartrazine on learning and memory functions in mice and rats, and the possible mechanisms involved.

Gao Y, Li C, Shen J, Yin H, An X, Jin H. Scientific and Technological College of Chemistry and Biology, Yantai Univ., Yantai, PR China. J Food Sci. 2011 Aug;76(6):T125-9.