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Our "No Return Necessary"
Money-Back Guarantee

If you don’t like something of ours, guess what happens next?

No, we don’t request you deliver it to a PO box in the Gobi Desert by carrier pigeon. Nor do we ask you to fill a cursed inkwell with orc’s blood and demon saliva and then use it to complete reams of return forms written in ancient Cyrillic script.

We just . . . wait for it . . . give you your money back. Holy moo cows. And that means you can say "yes" now and decide later.

Will our energy drink supercharge your nervous system for explosive energy and maximum mental and physical performance?

No.

Will it crush fatigue and procrastination and give you an “unfair advantage” inside and outside of the gym?

Absolutely not.

But is it the only[1] Some popular energy drinks are naturally sweetened and flavored. Some contain the right mix of high-quality ingredients. Some provide clinically effective doses. But only our energy drink checks each of these boxes. naturally sweetened and flavored[2] While artificial sweeteners may not be as dangerous as some people claim, studies suggest that regular consumption of them may indeed be harmful to our health. That’s why we use the natural sweeteners stevia, monk fruit, and erythritol instead. energy drink with clinically effective doses[3] Every serving of our energy drink contains 3.57 grams of active ingredients that have been shown to be safe and effective in peer-reviewed scientific research. of 8 ingredients scientifically proven[4] Each active ingredient in our energy drink is backed by published scientific studies that show benefits in healthy humans. to increase energy, focus, mood, strength, and stamina?

And without the “caffeine crash” or other unwanted side effects?

Yes. Or your money back

  • 40 peer-reviewed scientific studies support the effectiveness of our energy drink’s precise combination of ingredients and doses[5] That’s 402 pages of scientific research that shows our energy drink works exactly like we say it does.
  • Naturally sweetened and flavored with no artificial sweeteners, flavors, food dyes, fillers, or other unnecessary junk[6] While these types of chemicals may not be as dangerous as some people claim, studies suggest that regular consumption of them may indeed be harmful to our health.
  • Analyzed for purity and potency in a state-of-the-art ISO 17025 accredited lab[7] Every can of our energy drink is guaranteed to provide exactly what the label claims and nothing else—no heavy metals, microbes, allergens, or other contaminants.
  • Clean and transparent label that shows exactly what’s in every serving and what’s not (no proprietary blends or hidden ingredients)[8] The "proprietary blend" is little more than a sneaky way to use tiny (ineffective) amounts of lots of ingredients and hope customers don't know any better.
  • Made in the USA with globally sourced ingredients in FDA-inspected facilities that adhere to Current Good Manufacturing Practice standards

Our energy drink is also backed by our “No Return Necessary” money-back guarantee that works like this:

If you don’t absolutely love it, just let us know, and we’ll give you a full refund on the spot. No forms or returns necessary.

So order now, try it risk free, and see for yourself why we believe it’s the perfect clean energy beverage.

Will our energy drink supercharge your nervous system for explosive energy and maximum mental and physical performance?

No.

Will it crush fatigue and procrastination and give you an “unfair advantage” inside and outside of the gym?

Absolutely not.

But is it the perfect alternative to coffee or pre-workout when you want a boost to get through a workout or afternoon slump?

And without the “caffeine crash” or other unwanted side effects?

Yes. Or your money back.

  • Clean and transparent label that shows exactly what’s in every serving and what’s not (no proprietary blends or hidden ingredients)[8] The "proprietary blend" is little more than a sneaky way to use tiny (ineffective) amounts of lots of ingredients and hope customers don't know any better.
  • Made in the USA with globally sourced ingredients in FDA-inspected facilities that adhere to Current Good Manufacturing Practice standards
  • Backed by our “No Return Necessary” money-back guarantee that works like this: If you don’t absolutely love our energy drink, just let us know, and we’ll give you a full refund on the spot. No forms or returns necessary.

So order now, try it risk free, and see for yourself why we believe it’s the perfect clean energy beverage.

Notice to California Consumers

WARNING: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Legion Energy Drink Ingredients (3,577 milligrams per serving)

PurCaf® Natural and Organic Caffeine (150 milligrams per serving)

Caffeine is a naturally occurring substance found in many plants native to Africa, East Asia, and South America, including various kinds of tea, cocoa, and coffee.

PurCaf® is an organic, patented form of caffeine extracted from non-GMO green coffee beans using a proprietary clean-water process.

Naturally derived caffeine tastes significantly better than its synthetic counterpart, and anecdotally, many people report that it provides a "smoother" boost of energy, possibly due to beneficial compounds like chlorogenic acids and antioxidants found in natural caffeine but absent in synthetic versions.

Caffeine’s primary effects in the body are to stimulate the central nervous system and block the activity of another chemical—adenosine—that causes tiredness.

Research shows that supplementation with PurCaf® caffeine . . .

The clinically effective dose of caffeine for enhancing energy, focus, and performance is between 50 milligrams and 6 milligrams per kilogram of body weight.[27][28][29]

Caffeine

Suntheanine® L-Theanine (150 milligrams per serving)

L-theanine is an amino acid found primarily in tea that helps balance the levels of two chemicals in the brain—glutamate and GABA—that transmit nerve impulses and affect mood, cognitive performance, and more.

Suntheanine® is a patented form of L-theanine that’s the most clinically proven form on the market, with over 200 peer-reviewed studies supporting its efficacy.

Research shows that supplementation with Suntheanine® L-theanine . . .

  • Reduces the effects of mental stress[30]
  • Promotes relaxation[31]
  • Improves mood, memory performance, and attention (when paired with caffeine)[32][33][34][35]
  • Increases the production of nitric oxide (which improves blood flow)[36]

The clinically effective dose of L-theanine when combined with caffeine is between a ratio of 1:1 and 2:1 theanine to caffeine.

Caffeine

Cognizin® Citicoline (250 milligrams per serving)

Citicoline is a chemical that occurs naturally in the brain and increases levels of another chemical called phosphatidylcholine, which is vital for brain health and function.

Citicoline can also increase levels of a neurotransmitter known as acetylcholine, which is involved in learning and muscular contraction.

Cognizin® is a patented form of citicoline that’s the only form studied in healthy adults and supported by 16 years of clinical research.

Research shows that supplementation with Cognizin® citicoline . . .

  • Improves focus and memory[37][38]
  • Boosts attention and mental processing speed[39]
  • Mitigates cognitive decline as we age[40][41][42]

The clinically effective dose of citicoline is between 250 and 500 milligrams.

Caffeine

Taurine (2,000 milligrams per serving)

Taurine is an amino acid found primarily in seafood and meat that, unlike most amino acids, isn’t used to build proteins.

Rather, it plays an important role in cardiovascular and muscle function by protecting cells from oxidative stress and regulating the release of neurotransmitters.

Research shows that supplementation with taurine . . .

  • Improves focus, attention, and reasoning when combined with caffeine[43][44]
  • Helps minimize unwanted side effects of caffeine (like jitters)[45]
  • Helps prevent a “sugar crash” by slowing the release of glucose into the blood[46][47]

The clinically effective dose of taurine is 1-to-6 grams per day, with the majority of benefits in the range of ~1-to-3 grams.

Caffeine

B Vitamin Complex (27.4 milligrams per serving)

B vitamins are a category of naturally-occurring substances that cells need to turn food into energy. They also affect mood, feelings of wellness, and brain, nerve, and cardiovascular function.

Although B vitamins don’t directly increase energy levels in the same way as a stimulant like caffeine, many people report feeling more energized when supplementing with B vitamins. This is likely because B vitamins are required for many bodily processes that influence energy production, and thus, by increasing the availability of B vitamins, such processes can function more effectively.

Research shows that supplementation with B vitamins (particularly vitamins B2, B3, B6, and B12) . . .

  • Reduces stress[48]
  • Improves mental clarity, energy, and focus[49]
  • Boosts cognitive function and memory[50][51]
  • Improves mood and energy levels[52][53]

There is no established clinically effective dose of B vitamins, but the ones thought to most improve energy, mood, and cognitive function are B2, B3, B6, and B12 in the amounts contained in our energy drink.

Caffeine

Naturally Sweetened & Flavored

While artificial sweeteners may not be as dangerous as some people claim, studies suggest that regular consumption of these chemicals may indeed be harmful to our health.[54][55][56][57][58][59]

That’s why we use the natural sweeteners stevia and erythritol instead. Studies show that these ingredients are not only safe but can also confer several health benefits, including better nutrient absorption, healthy cholesterol and inflammation levels, and more.[60][61][62][63]

No Artificial Food Dyes or Other Chemical Junk

No Artificial Food Dyes, Fillers, or Other Unnecessary Junk

As with artificial sweeteners, artificial food dyes aren’t a hazard per se, but studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.[64][65][66][67][68]

No Artificial Food Dyes or Other Chemical Junk

Lab Tested for Potency & Purity

Every can of our energy drink is analyzed in a state-of-the-art ISO 17025 accredited lab to verify what is and isn’t in it. That way, you know exactly what you’re getting and putting into your body.

Lab Tested for Potency & Purity
Energy Drink Certificate of Analysis

See how Legion energy drinks compare to the rest.

  • Active Ingredients
  • Clinically Effective Ingredients & Doses
  • Caffeine
  • L-Theanine
  • Citicoline
  • Taurine
  • Vitamin B Complex
  • Naturally Sweetened & Flavored
  • Third-Party Lab Tested
  • Labdoor Certified Brand
  • Price Per Can

  • Legion
    Energy Drink

    Legion Energy Drink
  • 3,577 mg
    per serving
  • true
  • 150 mg
    per serving
  • 150 mg
    per serving
  • 250 mg
    per serving
  • 2,000 mg
    per serving
  • 27.4 mg
    per serving
  • true
  • true
  • true
  • $

  • Ghost
    Energy

    Ghost Energy Drink
  • 2,492 mg
    per serving
  • false
  • 200 mg
    per serving
  • false
  • false
  • 1,000 mg
    per serving
  • 17.7 mg
    per serving
  • false
  • questionable
  • false
  • $2.50

  • Cellucor C4
    Energy Drink

    Cellucor C4 Energy Drink
  • close
    (proprietary blend)

    A proprietary blend is a group of ingredients that lists their names but not amounts, making it impossible to know if the dosages are at clinically effective levels.
  • false
  • 200 mg
    per serving
  • false
  • false
  • false
  • 36 mg
    per serving
  • false
  • questionable
  • false
  • $2.33

  • Red Bull
    Sugar Free

    Red Bull Sugar Free Energy Drink
  • close
    (proprietary blend)

    A proprietary blend is a group of ingredients that lists their names but not amounts, making it impossible to know if the dosages are at clinically effective levels.
  • false
  • 114 mg
    per serving
  • false
  • false
  • close
    (proprietary blend)

    A proprietary blend is a group of ingredients that lists their names but not amounts, making it impossible to know if the dosages are at clinically effective levels.
  • 31.85 mg
    per serving
  • false
  • questionable
  • false
  • $2.13

The #1 brand of all-natural sports supplements.

Over 5+ million bottles sold to over 1+ million customers who have left us over 45,000 5-star reviews.

Clinically Effective Doses
Clinically Effective Ingredients & Doses

Every ingredient and dose in our energy drink is backed by peer-reviewed scientific research demonstrating clear benefits.

Naturally Sweetened & Flavored
Naturally Sweetened & Flavored

Our energy drink contains no artificial sweeteners or flavors, food dyes, fillers, or other unnecessary junk.

Total Label Transparency
100% Clean & Transparent Label

Our energy drink contains no hidden ingredients or proprietary blends, so you know exactly what (and what amount) is in every serving.

Lab Tested
Third-Party Lab Tested

Our energy drink is tested by third-party labs for heavy metals, microbes, allergens, and other contaminants to ensure it meets FDA purity standards.

Made in USA
Made in the USA

Our energy drink is made in America with globally sourced ingredients in FDA-inspected facilities that adhere to Current Good Manufacturing Practice standards.

100% Money-Back-Guarantee
"No Return Necessary"
Money-Back Guarantee

If you don't absolutely love our energy drink, you get a prompt and courteous refund. No forms or returns necessary.

Trusted by scientists, doctors, and everyday fitness folk alike.

Previous
  • Sal Di Stefano, Justin Andrews, and Adam Schafer

    "When it comes to quality and integrity, Legion is among the best. Their products only include ingredients that are backed by research and in doses that are proven to be effective in scientific studies."

    Sal Di Stefano, Justin Andrews, and Adam Schafer

    Hosts of The Mind Pump Podcast
  • Dr. Bill Campbell, PhD

    "Legion is science-based at its core. Not only do they dose all of their products based on the clinical doses proven to be effective by scientific studies, they go above and beyond the their competitors by funding new research."

    Dr. Bill Campbell, PhD

    Professor of Exercise Science at University of South Florida
  • Jordan Syatt

    "Legion is a tremendous company run by people I trust and respect. The quality of their supplements is second to no one. And while I don’t use many supplements, the only ones I do come from Legion."

    Jordan Syatt

    Strength and Nutrition Coach
  • Dr. Spencer Nadolsky, MD

    "There are a lot of sleazy supplement companies out there, but Legion is not one of them. Their products are free of fillers and inactive ingredients and they take the time (and money) to test them with independent labs to ensure you're getting what you pay for."

    Dr. Spencer Nadolsky, MD

    Board-Certified Family Medicine Physician and a Diplomate of the American Board of Obesity Medicine
  • Menno Henselmans, MS

    "Legion consults with nutrition experts to make honest, science-based products and then proves they're genuine with independent lab work. That's how all supplement companies should operate."

    Menno Henselmans, MS

    Founder of Bayesian Bodybuilding, Published Scientist, and Physique Coach
  • Kurtis Frank

    "With Legion, you really do get what you pay for. Each and every product is packed with effective doses of effective ingredients, and what’s on the label is what's actually in the bottle."

    Kurtis Frank

    Co-Founder and Former Lead Researcher & Writer of Examine.com
  • James Krieger, MS

    "There are three reasons I like Legion. First, they use ingredients backed by independent, peer-reviewed scientific studies. Second, the quality of their supplements exceeds many in the industry and you know you’re getting what’s on the label. Third, Mike Matthews is a solid evidence-based guy who doesn’t over-hype."

    James Krieger, MS

    Published Scientist, Author, and Speaker
  • Chris Barakat, MS

    "Legion is the only company doing everything right. They make effective products that are backed by scientific evidence, properly dose all of their ingredients, source every ingredient from the highest-quality sources, and are transparent about exactly what goes in each and every product."

    Chris Barakat, MS

    Published Scientist and Physique Coach
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+References

9. Exercise and sport performance with low doses of caffeine.

Spriet LL. Sports Med. 2014;44 Suppl 2(Suppl 2):S175-S184. doi:10.1007/s40279-014-0257-8.↑

10. A review of caffeine's effects on cognitive, physical and occupational performance.

McLellan TM, Caldwell JA, Lieberman HR. Neurosci Biobehav Rev. 2016;71:294-312. doi:10.1016/j.neubiorev.2016.09.001.↑

11. Caffeine to optimize cognitive function for military mission-readiness: a systematic review and recommendations for the field.

Crawford C, Teo L, Lafferty L, et al. Nutr Rev. 2017;75(suppl_2):17-35. doi:10.1093/nutrit/nux007.↑

12. Caffeine improves reaction time, vigilance and logical reasoning during extended periods with restricted opportunities for sleep.

Kamimori GH, McLellan TM, Tate CM, Voss DM, Niro P, Lieberman HR. Psychopharmacology (Berl). 2015;232(12):2031-2042. doi:10.1007/s00213-014-3834-5.↑

13. Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers.

Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J. Am J Clin Nutr. 1990;51(5):759-767. doi:10.1093/ajcn/51.5.759.↑

14. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.

Beck TW, Housh TJ, Schmidt RJ, et al. J Strength Cond Res. 2006;20(3):506-510. doi:10.1519/18285.1.↑

15. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis.

Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8.↑

16. The effects of caffeine ingestion on isokinetic muscular strength: A meta-analysis.

Grgic J, Pickering C. J Sci Med Sport. 2019;22(3):353-360. doi:10.1016/j.jsams.2018.08.016.↑

17. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.

Grgic J, Trexler ET, Lazinica B, Pedisic Z. J Int Soc Sports Nutr. 2018;15:11. Published 2018 Mar 5. doi:10.1186/s12970-018-0216-0.↑

18. Caffeine ingestion enhances Wingate performance: a meta-analysis.

Grgic J. Eur J Sport Sci. 2018;18(2):219-225. doi:10.1080/17461391.2017.1394371.↑

19. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.

Beck TW, Housh TJ, Schmidt RJ, et al. J Strength Cond Res. 2006;20(3):506-510. doi:10.1519/18285.1.↑

20. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis.

Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8.↑

21. Acute effect of caffeine consumption on isotonic muscular strength and endurance: A systematic review and meta-analysis.

Polito MD, Souza DB, Casonatto J, Farinatti P. Sci Sports. 2016;31(3):119-128. doi:10.1016/J.SCISPO.2016.01.006.↑

22. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities.

Beck TW, Housh TJ, Schmidt RJ, et al. J Strength Cond Res. 2006;20(3):506-510. doi:10.1519/18285.1.↑

23. Effect of caffeine on sport-specific endurance performance: a systematic review.

Ganio MS, Klau JF, Casa DJ, Armstrong LE, Maresh CM. J Strength Cond Res. 2009;23(1):315-324↑

24. Establishing a relationship between the effect of caffeine and duration of endurance athletic time trial events: A systematic review and meta-analysis.

Shen JG, Brooks MB, Cincotta J, Manjourides JD. J Sci Med Sport. 2019;22(2):232-238. doi:10.1016/j.jsams.2018.07.022.↑

25. The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis [published correction appears in Sports Med. 2018 Aug 9;:].

Southward K, Rutherfurd-Markwick KJ, Ali A. Sports Med. 2018;48(8):1913-1928. doi:10.1007/s40279-018-0939-8.↑

26. The effects of different doses of caffeine on endurance cycling time trial performance.

Desbrow B, Biddulph C, Devlin B, Grant GD, Anoopkumar-Dukie S, Leveritt MD. J Sports Sci. 2012;30(2):115-120. doi:10.1080/02640414.2011.632431.↑

27. Effect of caffeine on sport-specific endurance performance: a systematic review.

Ganio MS, Klau JF, Casa DJ, Armstrong LE, Maresh CM. J Strength Cond Res. 2009;23(1):315-324. doi:10.1519/JSC.0b013e31818b979a.↑

28. A review of caffeine’s effects on cognitive, physical and occupational performance.

McLellan TM, Caldwell JA, Lieberman HR. Neurosci Biobehav Rev. 2016;71:294-312. doi:10.1016/J.NEUBIOREV.2016.09.001.↑

29. International society of sports nutrition position stand: caffeine and exercise performance.

Guest NS, VanDusseldorp TA, Nelson MT, et al. J Int Soc Sports Nutr. 2021;18(1). doi:10.1186/S12970-020-00383-4.↑

30. L-Theanine reduces psychological and physiological stress responses.

Kimura K, Ozeki M, Juneja LR, Ohira H. Biol Psychol. 2007;74(1):39-45. doi:10.1016/j.biopsycho.2006.06.006.↑

31. In Search of a Safe Natural Sleep Aid.

Rao TP, Ozeki M, Juneja LR. J Am Coll Nutr. 2015;34(5):436-447. doi:10.1080/07315724.2014.926153.↑

32. Psychological effects of dietary components of tea: caffeine and L-theanine.

Bryan J. Nutr Rev. 2008;66(2):82-90. doi:10.1111/j.1753-4887.2007.00011.x.↑

33. L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.

Einöther SJ, Martens VE, Rycroft JA, De Bruin EA. Appetite. 2010;54(2):406-409. doi:10.1016/j.appet.2010.01.003.↑

34. The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task. Brain Topogr.

Gomez-Ramirez M, Kelly SP, Montesi JL, Foxe JJ. Brain Topogr. 2009;22(1):44-51.↑

35. l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study.

Kahathuduwa CN, Dhanasekara CS, Chin SH, et al. Nutr Res. 2018;49:67-78. doi:10.1016/j.nutres.2017.11.002.↑

36. L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.

Siamwala JH, Dias PM, Majumder S, et al. J Nutr Biochem. 2013;24(3):595-605.↑

37. Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.

McGlade E, Locatelli A, Hardy J, et al. Food Nutr Sci. 2012;3(6):769-773. doi:10.4236/FNS.2012.36103.↑

38. Citicoline improves memory performance in elderly subjects.

Alvarez XA, Laredo M, Corzo D, et al. Methods Find Exp Clin Pharmacol. 1997;19(3):201-210.↑

39. The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.

McGlade E, Agoston AM, DiMuzio J, et al. J Atten Disord. 2019;23(2):121-134. doi:10.1177/1087054715593633↑

40. Citicoline improves verbal memory in aging.

Spiers PA, Myers D, Hochanadel GS, Lieberman HR, Wurtman RJ. Arch Neurol. 1996;53(5):441-448. doi:10.1001/archneur.1996.00550050071026.↑

41. A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence.

Brown ES, Gorman AR, Hynan LS. J Clin Psychopharmacol. 2007;27(5):498-502. doi:10.1097/JCP.0b013e31814db4c4.↑

42. Citicoline improves memory performance in elderly subjects.

Alvarez XA, Laredo M, Corzo D, et al. Methods Find Exp Clin Pharmacol. 1997;19(3):201-210.↑

43. An evaluation of a caffeinated taurine drink on mood, memory and information processing in healthy volunteers without caffeine abstinence.

Warburton DM, Bersellini E, Sweeney E. Psychopharmacology (Berl). 2001;158(3):322-328. doi:10.1007/s002130100884.↑

44. A taurine and caffeine-containing drink stimulates cognitive performance and well-being.

Seidl R, Peyrl A, Nicham R, Hauser E. Amino Acids. 2000;19(3-4):635-642. doi:10.1007/s007260070013.↑

45. Effects and Mechanisms of Taurine as a Therapeutic Agent.

Schaffer S, Kim HW. Biomol Ther (Seoul). 2018;26(3):225-241. doi:10.4062/biomolther.2017.251.↑

46. The Effect of Taurine on the Glucose Absorption in the Small Intestine.

Tsuchiya Y, Kawamata K. 2015:164. doi:10.11428/KASEI.67.0_164.↑

47. Effects of taurine on plasma glucose concentration and active glucose transport in the small intestine.

Tsuchiya Y, Kawamata K. Anim Sci J. 2017;88(11):1763-1767. doi:10.1111/asj.12829.↑

48. The effect of 90 day administration of a high dose vitamin B-complex on work stress.

Stough C, Scholey A, Lloyd J, Spong J, Myers S, Downey LA. Hum Psychopharmacol. 2011;26(7):470-476. doi:10.1002/hup.1229.↑

49. Thiamine supplementation mood and cognitive functioning.

Benton D, Griffiths R, Haller J. Psychopharmacology (Berl). 1997;129(1):66-71. doi:10.1007/s002130050163.↑

51. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.

Deijen JB, van der Beek EJ, Orlebeke JF, van den Berg H. Psychopharmacology (Berl). 1992;109(4):489-496. doi:10.1007/BF02247729.↑

52. Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time.

Skarupski KA, Tangney C, Li H, Ouyang B, Evans DA, Morris MC. Am J Clin Nutr. 2010;92(2):330-335. doi:10.3945/ajcn.2010.29413.↑

53. Vitamin B12 supplementation in treating major depressive disorder: a randomized controlled trial.

Syed EU, Wasay M, Awan S. Open Neurol J. 2013;7:44-48. Published 2013 Nov 15. doi:10.2174/1874205X01307010044.↑

54. Artificial Sweeteners: History and New Concepts on Inflammation.

Basson AR, Rodriguez-Palacios A, Cominelli F. Front Nutr. 2021;8:746247. Published 2021 Sep 24. doi:10.3389/fnut.2021.746247.↑

55. Non-caloric artificial sweeteners and the microbiome: findings and challenges.

Suez J, Korem T, Zilberman-Schapira G, Segal E, Elinav E. Gut Microbes. 2015;6(2):149-155. doi:10.1080/19490976.2015.1017700.↑

56. What made Canada become a country with the highest incidence of inflammatory bowel disease: could sucralose be the culprit?

Qin X. Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA. Can J Gastroenterol. 2011 Sep;25(9):511. ↑

57. Artificial Sweeteners Negatively Regulate Pathogenic Characteristics of Two Model Gut Bacteria, E. coli and E. faecalis.

Shil A, Chichger H. Int J Mol Sci. 2021;22(10):5228. Published 2021 May 15. doi:10.3390/ijms22105228.↑

58. Artificial sweeteners induce glucose intolerance by altering the gut microbiota.

Suez J, Korem T, Zeevi D, et al. Nature. 2014;514(7521):181-186. doi:10.1038/nature13793.↑

59. High-intensity sweetener consumption and gut microbiome content and predicted gene function in a cross-sectional study of adults in the United States.

Frankenfeld CL, Sikaroodi M, Lamb E, Shoemaker S, Gillevet PM. Ann Epidemiol. 2015;25(10):736-42.e4. doi:10.1016/j.annepidem.2015.06.083.↑

60. Steviol glycosides from Stevia: biosynthesis pathway review and their application in foods and medicine.

Yadav SK, Guleria P. CSIR-Institute of Himalayan Bioresource Technology, Palampur, 176061, HP, India. Crit Rev Food Sci Nutr. 2012;52(11):988-98. ↑

61. Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana.

Shivanna N, Naika M, Khanum F, Kaul VK. Department of Applied Nutrition, Defence Food Research Laboratory, Mysore, India. J Diabetes Complications. 2013 Mar-Apr;27(2):103-13. ↑

62. Safety evaluation of certain food additives.

World Health Organization. WHO Press; 2006. Available at: http://whqlibdoc.who.int/publications/2006/9241660546_eng.pdf. Accessed January 24, 2019. ↑

63. Effects of Stevia rebaudiana (Bertoni) extract and N-nitro-L-arginine on renal function and ultrastructure of kidney cells in experimental type 2 Diabetes.

Ozbayer C, Kurt H, Kalender S, Ozden H, Gunes HV, Basaran A, Cakmak EA, Civi K, Kalender Y, Degirmenci I. Department of Medical Biology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey. J Med Food. 2011 Oct;14(10):1215-22. ↑

64. Toxicological significance of azo dye metabolism by human intestinal microbiota.

Feng J, Cerniglia CE, Chen H. Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, AR , USA. Front Biosci (Elite Ed). 2012 Jan 1;4:568-86. ↑

65. Artificial food dyes and attention deficit hyperactivity disorder.

Kanarek RB. Department of Psychology, Tufts University, Medford, Massachusetts, USA. Nutr Rev. 2011 Jul;69(7):385-91. ↑

66. Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives.

Nigg JT, Lewis K, Edinger T, Falk M. Oregon Health and Science University, Portland, OR, USA. J Am Acad Child Adolesc Psychiatry. 2012 Jan;51(1):86-97.e8. ↑

67. Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial.

McCann D, Barrett A, Cooper A, Crumpler D, Dalen L, Grimshaw K, Kitchin E, Lok K, Porteous L, Prince E, Sonuga-Barke E, Warner JO, Stevenson J. School of Psychology, Department of Child Health, University of Southampton, Southampton, UK. Lancet. 2007 Nov 3;370(9598):1560-7. ↑

68. Effect of food azo dye tartrazine on learning and memory functions in mice and rats, and the possible mechanisms involved.

Gao Y, Li C, Shen J, Yin H, An X, Jin H. Scientific and Technological College of Chemistry and Biology, Yantai Univ., Yantai, PR China. J Food Sci. 2011 Aug;76(6):T125-9. ↑

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