Simply let us know, and you'll get a full refund, no questions asked. And you don't even need to return anything.
So that means you can say "yes" now and decide later.
Legion Berberine Ingredient (1,500 milligrams per serving)
Berberine (1,500 milligrams per serving)
Berberine is a naturally occurring substance found in several plants, including Berberis species and Coptis chinensis. It has long been used in Chinese and Ayurvedic medicine to support digestive and metabolic health.
Berberine activates AMPK—an enzyme that regulates how your cells use energy—which may help support metabolic health as well as healthy cholesterol and triglyceride levels.[6][7][8][9][10]
It may also increase energy expenditure by activating brown fat, a type of fat that burns energy to produce heat.[11]
Research shows that supplementation with berberine . . .
The clinically effective dose of berberine is between 1,000 and 1,500 milligrams per day, typically split into 2 or 3 doses.
No Artificial Food Dyes, Fillers, or Other Unnecessary Junk
Artificial food dyes and fillers may not be as dangerous as some people claim, but studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.[22][23][24][25][26]
That’s why we use natural coloring derived from fruits and other foods as well as naturally derived ingredients for enhancing shelf life and facilitating the manufacturing process.
Third-Party Lab Tested for Purity and Accuracy
Our berberine is third-party lab tested for purity and accuracy and certified to meet or exceed FDA safety guidelines.[27]
Made in the USA with Globally Sourced Ingredients
If you want to ensure the supplements you’re swallowing every day are safe and effective, you want to buy from a company that:
Sources ingredients from premium suppliers around the world (great supplements require great raw materials)
Tests all products for purity and accuracy in accredited laboratories (to conclusively verify safety and efficacy)
Manufactures in America, which has some of the strictest regulations in the world
And that’s exactly what we do here at Legion.
See how Legion Berberine compares to the rest.
Active Ingredient Per Serving
Clinically Effective Ingredient & Dose
Third-Party Lab-Tested for Purity
Labdoor™ Certified Brand
Price Per Serving
Price Per Gram
Legion Berberine
1,500 mg per serving
Thorne Berberine
200 mg per serving
$0.50
$2.50
Pure Encapsulations Berberine
550 mg per serving
$0.86
$1.56
Sports Research Berberine
500 mg per serving
$0.33
$0.67
The #1 brand of naturally sweetened and flavored sports supplements.
We’ve sold over 5 million bags and bottles to over 1 million customers in 169 countries who have left us over 55,000 5-star reviews.
Clinically Effective Ingredient and Dose
The active ingredient, form, and dose in our berberine is backed by peer-reviewed scientific research demonstrating clear benefits in healthy humans.
Total Label Transparency
We clearly list the dose of each ingredient on our berberine label—no proprietary blends or hidden ingredients—so you can verify our formulation’s validity and effectiveness.
Third-Party Lab Tested for Purity and Accuracy
Our berberine is third-party lab tested for purity and accuracy and certified to meet or exceed FDA safety guidelines.
No Unnecessary Junk
Our berberine contains no artificial food dyes, fillers, or other unnecessary junk.
Made in the USA
Our berberine is made in America with globally sourced ingredients in NSF-certified, FDA-inspected facilities that adhere to Current Good Manufacturing Practice (cGMP) standards.
100% Money-Back Guarantee
If you don't absolutely love our berberine, you get a prompt and courteous refund. No forms or returns necessary.
Trusted by scientists, doctors, and everyday fitness folk alike.
"I most value Legion's integrity. Their products are based on the ingredients and doses shown to be effective by the scientific studies, and they don't just cite research but also fund it."
Dr. Bill Campbell, PhD, FISSN, CSCS
Professor of Exercise Science, University of South Florida Chair of Scientific Advisory Board
"I recommend Legion because they're transparent about what's in their products, they prioritize evidence-based ingredients and dosing, and they use third-party testing."
Dr. Jessie Hoffman, PhD, RD, CSDH
Assistant Professor of Human Nutrition, Winthrop University Scientific Advisory Board
"As a physician, I look for evidence, transparency, and consistency. Legion checks all three. I've used their products for over 7 years because their formulations reflect a level of rigor that's uncommon in this space."
Dr. Eugene Choi, MD
Chair of Radiology, Good Samaritan Hospital, Los Angeles Scientific Advisory Board
"I trust Legion's approach because every ingredient, dose, and formulation decision is grounded in research on what actually works in real-world application, not just what looks good on a label."
Dr. Katie Vasenina, PhD, CISSN
Professor of Exercise Science, University of Tampa Lead Formulation Scientist
"Legion is one of the few supplement companies with transparency and integrity. You not only get what you pay for, you know what you're paying for and taking and why."
Dr. Alyssa Olenick, PhD, CISSN
Exercise, Metabolism, and Female Physiology Scientist
"I've used Legion products for years. It's rare to find a company that combines high-quality supplements with evidence-backed ingredients and fully transparent formulations."
Andres Ayesta, MS, RD, LD
Founder of Planos Nutrition Scientific Advisory Board
"Legion's commitment to transparency in their labeling and use of top-notch ingredients sets them apart from other supplement companies."
Dr. Stacie Barber PT, DPT, CSCS, FRCms, USAW
Founder of The Physio Fix
"As someone with a strong academic and research-heavy background, I feel Legion really “gets it.” I know that what I think I'm getting with their products is actually what I'm getting: ingredients and doses supported by evidence. I can buy and recommend anything from Legion without a second thought."
Dr. Kasey Jo Orvidas, PhD
Published Researcher and Health Coach
"Legion is a tremendous company run by people I trust and respect. The quality of their supplements is second to no one. And while I don't use many supplements, the only ones I do come from Legion."
Jordan Syatt
Strength and Nutrition Coach
"Legion consults with nutrition experts to make honest, science-based products and then proves they're genuine with independent lab work. That's how all supplement companies should operate."
Menno Henselmans, MS
Founder of Bayesian Bodybuilding, Published Scientist, and Physique Coach
The actual evidence? Real reviews from verified buyers.
Frequently Asked Questions
How do I use your berberine?
Take 1 capsule 3 times daily with food.
Can I take berberine on an empty stomach?
We recommend taking our berberine capsules with food and splitting the serving across the day.
This matches how berberine is commonly used in research and may be easier to tolerate than taking all 3 capsules at once.
What type of effects should I notice when I take your berberine?
Berberine’s effects usually aren’t immediately noticeable. Instead, it works behind the scenes to support metabolic health in multiple ways, so the main benefits are best assessed through changes in bloodwork over time.
What makes your berberine supplement different from other berberine supplements on the market?
Unlike many berberine supplements on the market, our berberine provides a clinically effective dose of berberine HCl—1,500 milligrams per serving—in easy-to-swallow capsules.
It’s also fully transparent, third-party tested for purity and potency, and made without artificial fillers, food dyes, or other unnecessary junk.
In short, it checks every box a high-quality berberine supplement should.
Can I take your berberine with other supplements or medications?
Check with your healthcare provider before taking berberine if you use any medications.
Berberine should be fine to take alongside most other Legion supplements, since there’s little meaningful overlap between their ingredients.
Is your berberine gluten-free, vegetarian, or vegan?
Yes.
What does the Prop65 warning on the labels mean?
Our products include a Proposition 65 warning in compliance with California’s regulatory guidelines, which are among the most stringent and sweeping in the world.
A Proposition 65 warning does not indicate whether a product is safe or unsafe. Rather, Proposition 65 is a consumer notification law in California that requires warnings to inform consumers about the presence of one or more of over 900 substances in various types of products. These substances include naturally occurring and ubiquitous compounds, even when present at levels below those known to cause harm.
Our berberine contains the exact ingredient, form, and dose used in peer-reviewed scientific research demonstrating clear benefits in healthy humans.↑
60 peer-reviewed scientific studies support our berberine’s ingredient and dose. That’s 418 pages of scientific research that shows our berberine works the way we say it does.↑
View Supplement Facts↑
View Supplement Facts↑
That’s 418 pages of scientific research that shows our berberine works the way we say it does.↑
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That's why we exclusively use ingredients and doses shown to work in peer-reviewed scientific studies on healthy men and women.↑
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That's why we exclusively use ingredients and doses shown to work in peer-reviewed scientific studies on healthy men and women.↑
The proprietary blend is little more than a sneaky way to use tiny (ineffective) amounts of lots of ingredients and hope customers don’t know any better.
Every dose listed. For every ingredient. In every product. Anything else is unacceptable.↑
The proprietary blend is little more than a sneaky way to use tiny (ineffective) amounts of lots of ingredients and hope customers don’t know any better.
Every dose listed. For every ingredient. In every product. Anything else is unacceptable.↑
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every batch and guarantee our products provide exactly what the labels claim—and nothing else.
With Legion, you can be certain that what you're putting into your body is truly safe and effective.
↑
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every batch and guarantee our products provide exactly what the labels claim—and nothing else.
With Legion, you can be certain that what you're putting into your body is truly safe and effective.
Gao Y, Li C, Shen J, Yin H, An X, Jin H. J Food Sci. 2011;76(6):T125-T129. doi:10.1111/j.1750-3841.2011.02267.x.↑
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA).↑
Many companies use shipping and handling fees to increase their profit margins, but here at Legion, we hate profits, so our shipping is free!
Okay, so we do dig on profits, but we also go in for happy customers, and free shipping works like gangbusters. So, if it's your first order and you live in the United States, your order ships free. And if you're a returning customer, your order ships free when it's over $80.
And if you're not happy with your purchase?
Simply let us know, and you'll get a full refund, no questions asked. And you don't even need to return anything.
So that means you can say “yes” now and decide later.
Why the $199 minimum purchase amount for free shipping?
To quench our piggish lust for grubby profits in the eternal service of the dread lord Mammon?
Kind of. But not really. Because here's the truth:
Single-item orders are so blasted expensive to ship that we make very little profit on them. And no profits make the bean counters lose their marbles.
But when you order just one more item, it only costs us a few dollars more to ship both of them to you. Add a third item, and it's just a few more shekels to ship.
And that allows us to make a profit. Which keeps the bean counters happier than a hammer in a nail factory.
So, if it pleases your Grace, we humbly request your mercy and patronage notwithstanding the vexing free shipping minimum.
Why the $299 minimum purchase amount for free shipping?
To quench our piggish lust for grubby profits in the eternal service of the dread lord Mammon?
Kind of. But not really. Because here's the truth:
Single-item orders are so blasted expensive to ship that we make very little profit on them. And no profits make the bean counters lose their marbles.
But when you order just one more item, it only costs us a few dollars more to ship both of them to you. Add a third item, and it's just a few more shekels to ship.
And that allows us to make a profit. Which keeps the bean counters happier than a hammer in a nail factory.
So, if it pleases your Grace, we humbly request your mercy and patronage notwithstanding the vexing free shipping minimum.
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That's why we exclusively use ingredients and doses shown to work in peer-reviewed scientific studies on healthy men and women.
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That's why we exclusively use ingredients and doses shown to work in peer-reviewed scientific studies on healthy men and women.
While artificial food dyes and fillers may not be as dangerous as some people claim, studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.
That’s why we use natural coloring derived from fruits and other foods as well as naturally derived ingredients for enhancing shelf life and facilitating the manufacturing process.
If you want to ensure the supplements you’re swallowing every day are safe and effective, you want to buy from a company that:
Sources ingredients from premium suppliers around the world (great supplements require great raw materials)
Tests all products for purity and potency in accredited third-party laboratories (to conclusively verify safety and efficacy)
Manufactures final products in America (which has some of the strictest regulations in the world)
Which is exactly what we do here at Legion.
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA).
Berberine is lab-tested for purity and accuracy and certified to contain no heavy metals, microbes, allergens, or other contaminants or banned substances
While artificial sweeteners, food dyes, and fillers may not be as dangerous as some people claim, studies suggest that regular consumption of these chemicals may indeed be harmful to our health.
That’s why we use natural sweeteners like stevia, allulose, and monk fruit instead as well as natural coloring and flavoring derived from fruits and other foods.
Research shows that these ingredients are not only safe but can also confer several health benefits, such as supporting weight management, antioxidant activity, digestive health, and more.
The proprietary blend is little more than a sneaky way to use tiny (ineffective) amounts of lots of ingredients and hope customers don’t know any better.
Every dose listed. For every ingredient. In every product. Anything else is unacceptable.
While artificial food dyes and fillers may not be as dangerous as some people claim, studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.
That’s why we use natural coloring derived from fruits and other foods as well as naturally derived ingredients for enhancing shelf life and facilitating the manufacturing process.
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That’s why we exclusively use ingredients and doses shown to be effective in peer-reviewed scientific studies on healthy men and women.
While artificial food dyes and fillers may not be as dangerous as some people claim, studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.
That’s why we use natural coloring derived from fruits and other foods as well as naturally derived ingredients for improving texture, enhancing shelf life, and facilitating the manufacturing process.
Not happy with your purchase?
Simply let us know, and you'll get a full refund, no questions asked. And you don't even need to return anything.
So that means you can say "yes" now and decide later.
Every active ingredient, form, and dose in This product is backed by peer-reviewed scientific research demonstrating clear benefits in healthy humans.
The ingredient, form, and dose in This product is backed by peer-reviewed scientific research demonstrating clear benefits in healthy humans.
Many supplement ingredients lack scientific validation in humans—we aren't large rodents, after all.
And even when ingredients have proven benefits, they're often used in doses too small to be effective.
That's why we exclusively use ingredients and doses shown to work in peer-reviewed scientific studies on healthy men and women.
The active ingredient, form, and dose in our creatine is backed by peer-reviewed scientific research demonstrating clear benefits in healthy humans.
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient in a third-party lab for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA).
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient in a third-party lab for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA) and World Anti Doping Agency (WADA).
Wait! Want to save 50% on your order of Legion supplements?
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Buy one supplement, get one 50% off when you use code LEGION10 at checkout.
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Waiver and Release of Liability
In consideration of the services and/or products offered by Legion Athletics, Inc. (“Legion”) including, but not limited to, nutrition plans, exercise routines and coaching, and in addition to the payment of any fee or charge:
I knowingly and voluntarily enter into this waiver and release of liability and hereby waive any and all rights, claims or causes of action of any kind whatsoever arising out of my use of Legion’s services and/or products, and I hereby release and hold harmless Legion and its consultants, officers, contractors, agents, owners and employees from any and all responsibility, liability, cost and expenses, including for injuries, damages or disorders (physical, metabolic, or otherwise), resulting from my use of Legion’s services and/or products.
I understand that fitness activities including, but not limited to, strength, flexibility, and cardiovascular exercise, with or without the use of equipment, are potentially hazardous activities that involve a risk of injury and even death, and I am voluntarily participating in these activities and using equipment and machinery with knowledge of the risks involved. I hereby agree to assume and accept any and all risks of injury or death related to said fitness activities.
I understand Legion’s services and products are not meant to treat or manage any health conditions or circumstances, and I acknowledge that Legion has recommended I obtain a healthcare provider’s approval for my use of Legion’s services and/or products, through regular physical examination(s) and/or consultation. I acknowledge that I have obtained my healthcare provider’s approval or have decided to use Legion’s services and/or products without such approval and hereby assume all responsibility for my use of said services and/or products.
I understand that results from using Legion’s products and/or services are not guaranteed, and I agree to not hold Legion liable for any outcomes or lack thereof.
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Legion's Scientific Review Process
Legion's content is fact-checked and reviewed by a team of scientific, medical and subject-matter experts to ensure everything we publish is evidence based, trustworthy, and current.
If you don’t absolutely love this product, you get a prompt and courteous refund. No forms or returns necessary.
Back
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient in a third-party lab for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA) and World Anti Doping Agency (WADA).
Berberine is lab-tested for purity and accuracy and independently certified by Labdoor™ to contain no heavy metals, microbes, allergens, or other contaminants or banned substances.
Did you know that some supplements contain dangerously high levels of toxins like lead, arsenic, and cadmium?
That’s why we rigorously test every ingredient in a third-party lab for heavy metals, microbes, allergens, and other contaminants, ensuring they meet the strict purity standards set by the U.S. Food and Drug Administration (FDA).
This product doesn’t just “contain natural ingredients”—every ingredient is naturally sourced from plants and animals. This product contains no artificial or synthetic sweeteners or flavors of any kind.
The ingredient, form, and dose in our product is backed by peer-reviewed scientific research demonstrating clear benefits in healthy humans.
Our product contains no artificial food dyes, fillers, or other unnecessary junk.
Because while these ingredients may not be as dangerous as some people claim, studies show they can cause negative effects in some people, including gastrointestinal toxicity and behavioral disorders.
That’s why we use natural coloring derived from fruits and other foods as well as naturally derived ingredients for enhancing shelf life and facilitating the manufacturing process.
Our scientific review board of nutritionists, dietitians, molecular biologists, doctors, and other accredited experts is responsible for reviewing every article, podcast, and video we produce to ensure they’re evidence based, accurate, trustworthy, and current.
Thanks to their connections, credentials, and academic experience, this team of MDs, PhDs, and other professionals has access to a wealth of research published in the largest and most prestigious journals in the world.
This allows them to not only review individual studies but also analyze the overall weight of the evidence on any and all topics related to diet, exercise, supplementation, and more.
If you feel that any of our content is inaccurate, misleading, out-of-date, or anything less than factual, please let us know in the comments section of the article in question.
Evidence Based
We follow a detailed, rigorous, multi-step process to create content that meets the highest standards of clarity, practicality, and scientific integrity.
First, our research associates provide our editorial team with accurate, up-to-date, proven scientific evidence.
Then, our editorial team uses this research to draft articles and outlines for podcasts and videos.
Finally, our scientific review board reviews the content to ensure all key information and claims are backed by high-quality scientific research and explained simply and precisely.
If you feel that any of our content is inaccurate, misleading, out-of-date, or anything less than factual, please let us know in the comments section of the article in question.
