Among all genres of supplements fat burners are surrounded by the most misinformation and blatant lies.
We’re going through an obesity epidemic and it’s reaching far more than just the US. I mean, a third of the entire damn world is overweight according to BMI. The. Entire. World.
It’s clearly an issue of habit formation, easy access to food that happens to be unhealthy but oh so delicious, and a society that places more value on mind than body leading to a lot more sedentary work than before.
But as long as there is science to suggest that a pill could help you lose fat, which there is, and people promising that their pills will make all the pain go away, then there’s going to be a market for them.
Don’t get me wrong, I do believe in the concept of fat burners. Even the best ones are far from magic bullets, but they can help speed the process up a bit…
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+ Scientific References
- Onakpoya IJ, Posadzki PP, Watson LK, Davies LA, Ernst E. The efficacy of long-term conjugated linoleic acid (CLA) supplementation on body composition in overweight and obese individuals: A systematic review and meta-analysis of randomized clinical trials. Eur J Nutr. 2012;51(2):127-134. doi:10.1007/s00394-011-0253-9
- Rahbar AR, Ostovar A, Derakhshandeh-Rishehri S-M, Janani L, Rahbar A. Effect of Conjugated Linoleic Acid as a Supplement or Enrichment in Foods on Blood Glucose and Waist Circumference in Humans: A Metaanalysis. Endocrine, Metab Immune Disord - Drug Targets. 2017;17(1). doi:10.2174/1570161115999170207113803
- Whigham LD, Watras AC, Schoeller DA. Efficacy of conjugated linoleic acid for reducing fat mass: A meta-analysis in humans. Am J Clin Nutr. 2007;85(5):1203-1211. doi:10.1093/ajcn/85.5.1203
- Risérus U, Vessby B, Ärnlöv J, Basu S. Effects of cis-9, trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. Am J Clin Nutr. 2004;80(2):279-283. doi:10.1093/ajcn/80.2.279
- Sneddon AA, Tsofliou F, Fyfe CL, et al. Effect of a conjugated linoleic acid and ω-3 fatty acid mixture on body composition and adiponectin. Obesity. 2008;16(5):1019-1024. doi:10.1038/oby.2008.41
- Joseph S V., Jacques H, Plourde M, Mitchell PL, McLeod RS, Jones PJH. Conjugated Linoleic Acid Supplementation for 8 Weeks Does Not Affect Body Composition, Lipid Profile, or Safety Biomarkers in Overweight, Hyperlipidemic Men. J Nutr. 2011;141(7):1286-1291. doi:10.3945/jn.110.135087
- Chen SC, Lin YH, Huang HP, Hsu WL, Houng JY, Huang CK. Effect of conjugated linoleic acid supplementation on weight loss and body fat composition in a Chinese population. Nutrition. 2012;28(5):559-565. doi:10.1016/j.nut.2011.09.008
- Watras AC, Buchholz AC, Close RN, Zhang Z, Schoeller DA. The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Int J Obes. 2007;31(3):481-487. doi:10.1038/sj.ijo.0803437
- Blom WAM, Abrahamse SL, Bradford R, et al. Effects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women: A randomized controlled trial. Am J Clin Nutr. 2011;94(5):1171-1181. doi:10.3945/ajcn.111.020321
- Quatela A, Callister R, Patterson A, Macdonald-Wicks L. The energy content and composition of meals consumed after an overnight fast and their effects on diet induced thermogenesis: A systematic review, meta-analyses and meta-regressions. Nutrients. 2016;8(11). doi:10.3390/nu8110670
- Gurguis GN, Vitton BJ, Uhde TW. Behavioral, sympathetic and adrenocortical responses to yohimbine in panic disorder patients and normal controls. Psychiatry Res. 1997;71(1):27-39. doi:10.1016/s0165-1781(97)00041-3
- Bourin M, Baker GB, Bradwejn J. Neurobiology of panic disorder. J Psychosom Res. 1998;44(1):163-180. doi:10.1016/s0022-3999(97)00203-1
- Ostojic SM. Yohimbine: The effects on body composition and exercise performance in soccer players. Res Sport Med. 2006;14(4):289-299. doi:10.1080/15438620600987106
- Greenway FL, Bray GA. Regional fat loss from the thigh in obese women after adrenergic modulation. Clin Ther. 1987;9(6):663-669. https://www.ncbi.nlm.nih.gov/pubmed/2894247. Accessed January 28, 2020.
- Greenway FL, Bray GA, Heber D. Topical fat reduction. Obes Res. 1995;3 Suppl 4. doi:10.1002/j.1550-8528.1995.tb00228.x
- Ostojic SM. Yohimbine: The effects on body composition and exercise performance in soccer players. Res Sport Med. 2006;14(4):289-299. doi:10.1080/15438620600987106
- Greenway FL, Bray GA. Regional fat loss from the thigh in obese women after adrenergic modulation. Clin Ther. 1987;9(6):663-669. https://www.ncbi.nlm.nih.gov/pubmed/2894247. Accessed January 28, 2020.
- Ostojic SM. Yohimbine: The effects on body composition and exercise performance in soccer players. Res Sport Med. 2006;14(4):289-299. doi:10.1080/15438620600987106
- GALITZKY J, TAOUIS M, BERLAN M, RIVIÈRE D, GARRIGUES M, LAFONTAN M. α2‐Antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988;18(6):587-594. doi:10.1111/j.1365-2362.1988.tb01272.x
- Crespi F. Anxiolytics antagonize yohimbine-induced central noradrenergic activity: A concomitant in vivo voltammetry-electrophysiology model of anxiety. J Neurosci Methods. 2009;180(1):97-105. doi:10.1016/j.jneumeth.2009.03.007
- Lafontan M, Berlan M, Galitzky J, Montastruc JL. Alpha-2 adrenoceptors in lipolysis: α2 antagonists and lipid-mobilizing strategies. In: American Journal of Clinical Nutrition. Vol 55. ; 1992. doi:10.1093/ajcn/55.1.219s
- Haller CA, Jacob P, Benowitz NL. Enhanced stimulant and metabolic effects of combined ephedrine and caffeine. Clin Pharmacol Ther. 2004;75(4):259-273. doi:10.1016/j.clpt.2003.11.375
- Vukovich MD, Schoorman R, Heilman C, Jacob P, Benowitz NL. Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure. Clin Exp Pharmacol Physiol. 2005;32(1-2):47-53. doi:10.1111/j.1440-1681.2005.04152.x
- Astrup A, Lundsgaard C, Madsen J, Christensen NJ. Enhanced thermogenic responsiveness during chronic ephedrine treatment in man. Am J Clin Nutr. 1985;42(1):83-94. doi:10.1093/ajcn/42.1.83
- Cheng JT, Liu IM, Yen ST, Juang SW, Liu TP, Chan P. Stimulatory effect of D-ephedrine on beta3-adrenoceptors in adipose tissue of rats. Auton Neurosci. 2001;88(1-2):1-5. doi:10.1016/s1566-0702(01)00225-9
- Molnár D. Effects of ephedrine and aminophylline on resting energy expenditure in obese adolescents. Int J Obes Relat Metab Disord. 1993;17 Suppl 1:S49-52. http://www.ncbi.nlm.nih.gov/pubmed/8384181. Accessed January 28, 2020.
- Nielsen B, Astrup A, Samuelsen P, Wengholt H, Christensen NJ. Effect of physical training on thermogenic responses to cold and ephedrine in obesity. Int J Obes Relat Metab Disord. 1993;17(7):383-390. http://www.ncbi.nlm.nih.gov/pubmed/8395473. Accessed January 28, 2020.
- Ma G, Bavadekar SA, Davis YM, et al. Pharmacological effects of ephedrine alkaloids on human α1- and α2-adrenergic receptor subtypes. J Pharmacol Exp Ther. 2007;322(1):214-221. doi:10.1124/jpet.107.120709
- Pasman WJ, Westerterp-Plantenga MS, Saris WHM. The effectiveness of long-term supplementation of carbohydrate, chromium, fibre and caffeine on weight maintenance. Int J Obes. 1997;21(12):1143-1151. doi:10.1038/sj.ijo.0800528
- Astrup A, Breum L, Toubro S, Hein P, Quaade F. The effect and safety of an ephedrine/caffeine compound compared to ephedrine, caffeine and placebo in obese subjects on an energy restricted diet. A double blind trial. Int J Obes. 1992;16(4):269-277. https://www.ncbi.nlm.nih.gov/pubmed/1318281. Accessed January 28, 2020.
- Bangsbo J, Jacobsen K, Nordberg N, Christensen NJ, Graham T. Acute and habitual caffeine ingestion and metabolic responses to steady- state exercise. J Appl Physiol. 1992;72(4):1297-1303. doi:10.1152/jappl.1992.72.4.1297
- Astrup A, Toubro S, Cannon S, Hein P, Breum L, Madsen J. Caffeine: A double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr. 1990;51(5):759-767. doi:10.1093/ajcn/51.5.759
- Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E. Caffeine and coffee: Their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 1980;33(5):989-997. doi:10.1093/ajcn/33.5.989
- Graham TE, Spriet LL. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol. 1995;78(3):867-874. doi:10.1152/jappl.1995.78.3.867
- Ferre S, Ciruela F, Borycz J, et al. Adenosine A1-A2A receptor heteromers: New targets for caffeine in the brain. Front Biosci. 2008;13(6):2391-2399. doi:10.2741/2852
- Health Effects of Overweight and Obesity in 195 Countries over 25 Years. N Engl J Med. 2017;377(1):13-27. doi:10.1056/NEJMoa1614362