Ascend | Nootropic
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The Total Wellness Stack boosts your brain health and performance, plugs nutritional holes in your diet, and reduces the risk of disease and dysfunction.
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How much joy and satisfaction you get from life depends in large part on how well you can focus, think, and remember.
For example, these faculties determine . . .
How quickly you can learn new things and acquire new skills
How efficiently and productively you can work
How effectively you can communicate and connect with others
How you perceive and understand yourself, others, and the world around you
Highly functional cognitive abilities don’t necessarily come easy, either.
There are biological hurdles, of course, but environmental and lifestyle ones as well, including technological distractions, poor nutrition and sleep hygiene, stress, and sedentary living.
That’s why anyone who wants to optimize their mental health and performance should limit their exposure to always-on technologies, eat plenty of nutritious, relatively unprocessed foods, exercise regularly, and get enough sleep.
Supplementation can help as well, and that’s why we created Ascend.
It’s a 100% natural nootropic (“brain booster”) that enhances your focus, memory, mental speed, creativity, mood, and overall brain health.
That is, Ascend sharpens your mind, improves your memory, and lifts your mood by upgrading how your brain functions and repairs itself.
What’s more, it accomplishes this by providing your brain with vital nutrients instead of stimulants or other substances that can backfire when you stop taking them.
The reason Ascend is so effective is simple:
Every ingredient is backed by peer-reviewed scientific research and is included at clinically effective levels.
That means the ingredients and doses in Ascend are based on published scientific research demonstrating real benefits, not the restrictions of razor-thin production budgets or gluttonous profit margins.
In other words, while everyone claims to have the best nootropic supplement on the market, we can actually back it up with real science and real numbers.
So, if you want to banish “foggy brain” and be able to think faster, focus deeper, and feel better . . . you want to try Ascend today.
You won’t be disappointed.
In fact, if you don’t absolutely love Ascend, just let us know and we’ll give you a full refund on the spot. No form or return necessary.
You really can’t lose, so order now and get ready to enjoy a sharper mind, better memory, and higher spirits.Buy Now Learn More Click here to view Prop 65 WARNING.
Notice to California Consumers
WARNING: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.
Many nootropics target just one aspect of your brain chemistry, like neurotransmitter activity, or rely on stimulants to produce immediately noticeable effects.
This can provide benefits in the short term, but over time, can also undermine critical brain functions and result in unwanted side effects.
For example, many brain boosters contain a molecule known as huperzine-A, which blocks the activity of an enzyme known as acetylcholinesterase, and this, in turn, inhibits the breakdown of acetylcholine, a neurotransmitter involved in learning and muscular contraction.
This mechanism appears to improve learning and cognitive performance, but the evidence is limited.
Either way, huperzine-A isn’t something you’d want to take every day because the molecule’s half-life (the time it takes for half of it to be removed from the body) is about 12 hours. Thus, if you take huperzine-A daily, you’d essentially never stop blocking activity of the acetylcholinesterase enzyme.
While this may be helpful for treating certain medical conditions like Alzheimer’s, it wouldn’t be ideal for healthy people.
In fact, if you were to do this, the body may adapt by creating more acetylcholinesterase to restore balance to your brain chemistry. Then, your acetylcholine levels would crater once you stopped taking huperzine-A and produce “withdrawal symptoms” of sorts.
L-DOPA is another example of an ingredient found in many nootropics that shouldn’t be supplemented with willy-nilly.
It’s an amino acid created by your brain that’s used to create several chemicals including dopamine, epinephrine, and norepinephrine, and when supplemented with, L-DOPA increases dopamine levels in the brain.
That sounds nice until you realize that the more often you use a supplement like L-DOPA to boost dopamine levels, the more your brain becomes resistant to its effects in an attempt to maintain normalcy.
Thus, regular supplementation with L-DOPA can result in a period of abnormally low levels of dopamine once you stop using it—the opposite of what you were trying to accomplish in the first place.
Ascend is different.
Instead of trying to “hack” or “supercharge” your brain chemistry, It provides your brain with key building blocks that not only improve how your brain operates, but also how it repairs and reconstructs itself.
Let’s take a look at the formulation.
Alpha-glycerophosphocholine (also known as alpha-GPC and glycerophosphocholine) is a compound of two molecules: choline and glycerophosphate.
Choline is a nutrient that’s vital for brain health and function, and glycerophosphate is a substance found in the membrane of neurons that helps transport choline to the brain.
When ingested, alpha-GPC increases the activity of a chemical in the brain known as acetylcholine, which is used by nerves to communicate with each other, and provides the brain with glycerophosphate, which may improve its health and function.
This is why research shows that supplementation with alpha-GPC . . .
- Increases power output 
- Protects against cognitive decline as we age 
- Increases growth hormone levels 
The clinically effective dose of alpha-GPC is between 150 and 1,200 milligrams, with 250 to 500 milligrams sufficient for cognitive benefits and higher doses required for affecting dementia.
Ascend contains 300 milligrams of alpha-GPC per serving.
CDP-choline (also known as citicoline), is a chemical that occurs naturally in the brain and increases levels of another chemical called phosphatidylcholine, which is vital for brain health and function.
The clinically effective dose of CDP-choline is between 250 and 500 milligrams.
Ascend contains 300 milligrams of CDP-choline per serving.
Uridine monophosphate is a compound of two molecules: uridine and phosphoric acid.
Uridine is a substance known as a nucleotide that’s involved in the production of the genetic material ribonucleic acid (RNA) and that supports and enhances the growth and function of neurons (nerve cells).
Phosphoric acid is a substance that helps the body create phosphatidylcholine, which is an essential building block for neurons.
While human research on uridine is currently sparse, the data we do have suggests it can . . .
- Enhance neuron growth 
- Preserve memory by protecting the brain from damage
- Reduce mental fatigue 
- Reduce the time it takes to fall asleep 
- Improve sleep quality
The clinically effective dose of uridine monophosphate hasn’t been established yet, but 250 milligrams is the human equivalent of what has produced benefits in animal research.
Ascend contains 250 milligrams of uridine monophosphate per serving.
Bacopa monnieri is an herb that has long been used in traditional Ayurvedic medicine to aid memory and treat various neurological disorders.
It contains substances known as bacosides that stimulate the secretion of two types of chemicals in the brain known as brain growth factors (brain-derived neurotrophic factor or BDNF, and nerve growth factor or NGF), which help neurons connect, grow, and proliferate.
That’s why research shows that supplementation with bacopa monnieri . . .
- Improves memory and cognition 
- Enhances mood 
- Reduces stress and depressive symptoms
The clinically effective dose of bacopa monnieri is between 200 and 400 milligrams depending on its bacoside content.
Ascend contains 330 milligrams of bacopa monnieri (standardized to 50% bacosides) per serving.
Agmatine is a chemical produced by the brain and found in some fermented foods.
It helps helps protect nerve cells against damage and interacts with the pain and pleasure pathways in the brain.
While human research on agmatine is currently sparse, the data we do have suggests it can enhance the activity of serotonin in the brain, which can enhance mood, and reduce the depressive effects of stress.
The clinically effective dose of agmatine hasn’t been established yet, but the nootropic range appears to be between 1.6 and 6.4 milligrams per kilogram of body weight, or 110 to 440 milligrams for a 150-pound person.
Ascend contains 500 milligrams of agmatine per serving.
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Zhao Q, Tang XC. Eur J Pharmacol. 2002;455(2-3):101-107. doi:10.1016/S0014-2999(02)02589-X.↑
Sun QQ, Xu SS, Pan JL, Guo HM, Cao WQ. Acta Pharmacol Sin. 1999;20(7):601-603.↑
Li YX, Zhang RQ, Li CR, Jiang XH. Eur J Drug Metab Pharmacokinet. 2007;32(4):183-187. doi:10.1007/BF03191002.↑
Ziegenfuss T, Landis J, Hofheins J. J Int Soc Sports Nutr. 2008;5(Suppl 1):P15. doi:10.1186/1550-2783-5-S1-P15.↑
De Jesus Moreno Moreno M. Clin Ther. 2003;25(1):178-193. ↑
Kawamura T, Okubo T, Sato K, et al. Nutrition. 2012;28(11-12):1122-1126. doi:10.1016/j.nut.2012.02.011.↑
Marcus L, Soileau J, Judge LW, Bellar D. Journal of the International Society of Sports Nutrition. 2017;14:39. doi:10.1186/s12970-017-0196-5.↑
Erin McGlade, Allison Locatelli, Julia Hardy, Toshikazu Kamiya, Masahiko Morita, Koji Morishita, Yoichiro Sugimura, and Deborah Yurgelun-Todd. Food and Nutrition Sciences 3, no. 6 (2012): 769-73. doi: 10.4236/fns.2012.36103. ↑
Alvarez XA, Laredo M, Corzo D, et al. Methods Find Exp Clin Pharmacol. 1997;19(3):201-210. ↑
Spiers PA, Myers D, Hochanadel GS, Lieberman HR, Wurtman RJ. Arch Neurol. 1996;53(5):441-448. doi:10.1001/archneur.1996.00550050071026. ↑
Brown ES, Gorman AR, Hynan LS. J Clin Psychopharmacol. 2007;27(5):498-502. doi:10.1097/JCP.0b013e31814db4c4. ↑
McGlade E, Locatelli A, Hardy J, et al. - Food Nutr Sci. 2012;3(6):769-773. doi:10.4236/fns.2012.36103. ↑
Gibellini F, Smith TK. IUBMB Life. 2010;62(6):414-428. doi:10.1002/iub.337. ↑
Fagone P, Jackowski S. Biochim Biophys Acta - Mol Cell Biol Lipids. 2013;1831(3):523-532. doi:10.1016/j.bbalip.2012.09.009.↑
Phan C-W, David P, Wong K-H, Naidu M, Sabaratnam V. Gallyas F, ed. PLoS One. 2015;10(11):e0143004. doi:10.1371/journal.pone.0143004.↑
Koyuncuoglu T, Turkyilmaz M, Goren B, Cetinkaya M, Cansev M, Alkan T. Restor Neurol Neurosci. 2015;33(5):777-784. doi:10.3233/RNN-150549. ↑
Cansev M, Minbay Z, Goren B, et al. Neurosci Lett. 2013;542:65-70. doi:10.1016/j.neulet.2013.02.035.↑
Goren B, Cakir A, Ocalan B, et al. Brain Res. 2017;1659:81-87. doi:10.1016/j.brainres.2017.01.026.↑
Teather LA, Wurtman RJ. J Nutr. 2006;136(11):2834-2837. ↑
Honda K, Okano Y, Komoda Y, Inoue S. Neurosci Lett. 1985;62(1):137-141. doi:10.1016/0304-3940(85)90297-6.↑
Honda K, Komoda Y, Nishida S, et al. Neurosci Res. 1984;1(4):243-252.↑
Peth-Nui T, Wattanathorn J, Muchimapura S, et al. Evidence-Based Complement Altern Med. 2012;2012:1-10. doi:10.1155/2012/606424.↑
Morgan A, Stevens J. J Altern Complement Med. 2010;16(7):753-759. doi:10.1089/acm.2009.0342.↑
Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, Limpeanchob N, Norman Scholfield C. J Ethnopharmacol. 2014;151(1):528-535. doi:10.1016/j.jep.2013.11.008.↑
Pase MP, Kean J, Sarris J, Neale C, Scholey AB, Stough C. J Altern Complement Med. 2012;18(7):647-652. doi:10.1089/acm.2011.0367. ↑
Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. J Altern Complement Med. 2008;14(6):707-713. doi:10.1089/acm.2008.0018.↑
Morgan A, Stevens J. J Altern Complement Med. 2010;16(7):753-759. doi:10.1089/acm.2009.0342. ↑
Benson S, Downey LA, Stough C, Wetherell M, Zangara A, Scholey A. Phyther Res. 2014;28(4):551-559. doi:10.1002/ptr.5029. ↑
Freitas AE, Egea J, Buendia I, et al. Mol Neurobiol. 2016;53(5):3030-3045. doi:10.1007/s12035-015-9182-6.↑
Taksande BG, Kotagale NR, Tripathi SJ, Ugale RR, Chopde CT. Neuropharmacology. 2009;57(4):415-424. doi:10.1016/j.neuropharm.2009.06.035.↑
Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Pain Med. 2010;11(3):356-368. doi:10.1111/j.1526-4637.2010.00808.x.↑
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Ingredients & Use
To support cognitive health and performance, supplement with one serving of ASCEND every day, preferably with food. You can take a full serving all at once or split it into two equal doses taken several hours apart (we recommend that you try both ways and see which you like best).
Not intended for use by persons under the age of 18. Do not exceed recommended dose. Consult your physician prior to use if you are pregnant or nursing, or if you are at risk, have been diagnosed, or are being treated for high blood pressure, heart, kidney, or thyroid, anxiety, depression, seizure disorder, or stroke.
KEEP OUT OF REACH OF CHILDREN. STORE IN A COOL DRY PLACE AND AVOID EXCESSIVE HEAT.
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